SCHEMBL29377026

SCHEMBL29377026

CC(C)C[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)[C@@H](C)O

nearest known ligand 0.67

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 15/20 0.67
▸ IL23R Q5VWK5 3/20 0.62
▸ GHSR Q92847 2/20 0.61
▸ NPY2R P49146 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32662800 0.95 KISS1R (0.74) KISS1RIL23RGHSRNPY2R
SCHEMBL29383648 0.95 KISS1R (0.69) KISS1RIL23RGHSRNPY2R
SCHEMBL29725112 0.91 KISS1R (0.62) KISS1RIL23R
SCHEMBL31257039 0.90 IL1RN (0.65) KISS1RNPY2R
SCHEMBL30757406 0.90 IL1RN (0.63) KISS1RNPY2R
SCHEMBL30262062 0.89 KISS1R (0.67) KISS1RIL23RGHSRNPY2R
SCHEMBL30596141 0.88 IL23R (0.69) KISS1RIL23R
SCHEMBL29834938 0.88 NPY4R (0.65) KISS1RNPY2R
SCHEMBL29834946 0.88 NPY4R (0.65) KISS1RNPY2R
SCHEMBL31092866 0.88 IL23R (0.64) KISS1RIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015399-A1 SOLUBLE NPY2 RECEPTOR AGONISTS BOEHRINGER INGELHEIM INT (DE) 2026-01-15 — — US claimed
EP-4192853-A1 SOLUBLE NPY2 RECEPTOR AGONISTS Boehringer Ingelheim International GmbH (DE) 2023-06-14 — — EP claimed
CN-116171282-A Soluble NPY2 receptor agonists 勃林格殷格翰国际有限公司 2023-05-26 — — CN claimed
US-20220041678-A1 SOLUBLE NPY2 RECEPTOR AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2022-02-10 — — US claimed
WO-2022029231-A1 SOLUBLE NPY2 RECEPTOR AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2022-02-10 — — WO claimed
US-20260015399-A1 SOLUBLE NPY2 RECEPTOR AGONISTS BOEHRINGER INGELHEIM INT (DE) 2026-01-15 — — US disclosed
US-12391737-B2 Soluble NPY2 receptor agonists BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2025-08-19 — — US disclosed
EP-4192853-A1 SOLUBLE NPY2 RECEPTOR AGONISTS Boehringer Ingelheim International GmbH (DE) 2023-06-14 — — EP disclosed
CN-116171282-A Soluble NPY2 receptor agonists 勃林格殷格翰国际有限公司 2023-05-26 — — CN disclosed
US-20220041678-A1 SOLUBLE NPY2 RECEPTOR AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2022-02-10 — — US disclosed
WO-2022029231-A1 SOLUBLE NPY2 RECEPTOR AGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2022-02-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220041678-A1 SOLUBLE NPY2 RECEPTOR AGONISTS NPY2R, NPY1R, NPY5R KISS1R 171/4885IL23R 360/4885GHSR 36/4885
US-12391737-B2 Soluble NPY2 receptor agonists NPY2R, NPY1R, NPY5R KISS1R 171/4885IL23R 360/4885GHSR 36/4885
US-20260015399-A1 SOLUBLE NPY2 RECEPTOR AGONISTS NPY1R, NPY2R, NPY5R KISS1R 107/4885IL23R 383/4885GHSR 23/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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