SCHEMBL29378153

SCHEMBL29378153

O=C1c2ccccc2C(=O)c2c(F)c(F)cc(F)c21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.50
MEN1 O00255 6/20 0.46
KMT2A Q03164 6/20 0.46
MAOA P21397 5/20 0.46
MAPT P10636 5/20 0.46
KDM4E B2RXH2 3/20 0.46
MAPK1 P28482 2/20 0.46
RECQL P46063 2/20 0.46
ALDH1A1 P00352 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
MAOB P27338 2/20 0.46
CYP1A1 P04798 1/20 0.46
CYP3A4 P08684 1/20 0.46
HSPD1 P10809 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
ALOX12 P18054 1/20 0.46
ACHE P22303 1/20 0.46
BRCA1 P38398 1/20 0.46
MMP14 P50281 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21817042 0.82 TTR (0.40) TTRMEN1KMT2AMAOAMAPT
SCHEMBL3418850 0.80 MEN1 (0.55) TTRMEN1KMT2AMAOAMAPT
SCHEMBL6650819 0.80 MEN1 (0.55) TTRMEN1KMT2AMAOAMAPT
SCHEMBL6650083 0.80 MEN1 (0.43) TTRMEN1KMT2AMAOAMAPT
SCHEMBL29502783 0.78 MEN1 (0.42) TTRMEN1KMT2AMAOAMAPT
SCHEMBL6653111 0.78 MEN1 (0.42) TTRMEN1KMT2AMAOAMAPT
SCHEMBL3417192 0.78 TTR (0.53) TTRMEN1KMT2AMAOAMAPT
SCHEMBL3415942 0.75 MAPT (0.50) TTRMEN1KMT2AMAOAMAPT
SCHEMBL9810967 0.75 MEN1 (0.48) TTRMEN1KMT2AMAOAMAPT
Benzoquinone SCHEMBL10607259 0.72 MEN1 (0.46) TTRMEN1KMT2AMAOAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3982170-B1 OPTICAL SHEET AND OPTICAL COMPONENT SUMITOMO BAKELITE CO (JP) 2023-12-06 EP disclosed
EP-3907554-B1 OPTICAL SHEET AND OPTICAL COMPONENT SUMITOMO BAKELITE CO (JP) 2023-05-03 EP disclosed
US-11634579-B2 Resin composition, molded body, optical layer, cover member and moving body SUMITOMO BAKELITE CO., LTD. (JP) 2023-04-25 US disclosed
US-11402667-B2 Optical sheet and optical component SUMITOMO BAKELITE CO., LTD. (JP) 2022-08-02 US disclosed
US-11345132-B2 Optical sheet and optical component SUMITOMO BAKELITE CO., LTD. (JP) 2022-05-31 US disclosed
EP-3982170-A1 OPTICAL SHEET AND OPTICAL COMPONENT Sumitomo Bakelite Co.Ltd. (JP) 2022-04-13 EP disclosed
US-20220043283-A1 OPTICAL SHEET AND OPTICAL COMPONENT SUMITOMO BAKELITE CO., LTD. (JP) 2022-02-10 US disclosed