Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 3/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.48 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 8/20 | 0.47 |
| ▸ | TNK1 | Q13470 | 6/20 | 0.47 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22532669 | 1.00 | ADRA1D (0.52) | ADRA1DADRA1AADRA1BCRBNDDB1 | |
| SCHEMBL22533363 | 0.94 | ADRA1D (0.49) | ADRA1DADRA1AADRA1BCRBNDDB1 | |
| SCHEMBL22533066 | 0.90 | ADRA1D (0.46) | ADRA1DADRA1AADRA1BCRBNDDB1 | |
| SCHEMBL22533445 | 0.90 | ADRA1D (0.45) | ADRA1DADRA1AADRA1BCRBNDDB1 | |
| SCHEMBL22533091 | 0.89 | ADRA1D (0.48) | ADRA1DADRA1AADRA1BCRBNDDB1 | |
| SCHEMBL27454482 | 0.89 | ADRA1D (0.47) | ADRA1DADRA1AADRA1BCRBNDDB1 | |
| SCHEMBL27454480 | 0.89 | ADRA1D (0.47) | ADRA1DADRA1AADRA1BCRBNDDB1 | |
| SCHEMBL22533360 | 0.88 | ADRA1D (0.43) | ADRA1DADRA1AADRA1BCRBNDDB1 | |
| SCHEMBL22532983 | 0.88 | DRD4 (0.40) | ADRA1DADRA1AADRA1BCRBNDDB1 | |
| SCHEMBL22532696 | 0.86 | ADRA1D (0.41) | ADRA1DADRA1AADRA1BCRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4228624-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C4 Therapeutics, Inc. (US) | 2023-08-23 | — | — | EP | disclosed |
| EP-4192450-A1 | ADVANTAGEOUS THERAPIES FOR DISORDERS MEDIATED BY IKAROS OR AIOLOS | C4 Therapeutics, Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022081927-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C4 THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| WO-2022032132-A1 | ADVANTAGEOUS THERAPIES FOR DISORDERS MEDIATED BY IKAROS OR AIOLOS | C4 THERAPEUTICS, INC. (US) | 2022-02-10 | — | — | WO | disclosed |