SCHEMBL29379

SCHEMBL29379

Fc1ccc(-n2c3ccc(-n4c5ccccc5c5ccccc54)cc3c3cc(-n4c5ccccc5c5ccccc54)ccc32)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.55
KDM4E B2RXH2 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
JAK2 O60674 1/20 0.42
JAK3 P52333 1/20 0.42
ALDH1A1 P00352 1/20 0.41
METAP2 P50579 2/20 0.40
HKDC1 Q2TB90 2/20 0.39
GRIA1 P42261 1/20 0.38
CACNG8 Q8WXS5 1/20 0.38
CACNG2 Q9Y698 1/20 0.38
CYP1A2 P05177 1/20 0.38
USP14 P54578 1/20 0.37
CYP19A1 P11511 1/20 0.37
PMM2 O15305 1/20 0.37
MPI P34949 1/20 0.37
RAB9A P51151 1/20 0.37
PHOSPHO1 Q8TCT1 1/20 0.37
APOBEC3G Q9HC16 1/20 0.37
REN P00797 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8739922 0.91 ATM (0.60) ATMKDM4EL3MBTL1JAK2JAK3
SCHEMBL29385 0.90 KDM4E (0.67) ATMKDM4EL3MBTL1JAK2JAK3
SCHEMBL16848794 0.90 KDM4E (0.67) ATMKDM4EL3MBTL1ALDH1A1CYP1A2
SCHEMBL19721759 0.90 KDM4E (0.67) ATMKDM4EL3MBTL1ALDH1A1CYP1A2
SCHEMBL29457635 0.90 KDM4E (0.67) ATMKDM4EL3MBTL1ALDH1A1CYP1A2
SCHEMBL21578475 0.90 KDM4E (0.67) ATMKDM4EL3MBTL1ALDH1A1CYP1A2
SCHEMBL15436035 0.89 KDM4E (0.52) ATMKDM4EL3MBTL1JAK2JAK3
SCHEMBL16405429 0.88 KDM4E (0.43) ATMKDM4EL3MBTL1JAK2JAK3
SCHEMBL8739912 0.87 KDM4E (0.48) ATMKDM4EL3MBTL1JAK2JAK3
SCHEMBL24531917 0.86 L3MBTL1 (0.75) ATMKDM4EL3MBTL1JAK2JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10644243-B2 N-phenyl triscarbazole NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2020-05-05 US disclosed
EP-2609080-B1 N-PHENYL TRISCARBAZOLE SOLVAY (BE) 2016-03-30 EP disclosed
EP-2609080-A1 N-PHENYL TRISCARBAZOLE Solvay SA (BE) 2013-07-03 EP disclosed
EP-2433928-A1 N-phenyl triscarbazole Solvay SA (BE) 2012-03-28 EP disclosed
WO-2012025510-A1 N-PHENYL TRISCARBAZOLE SOLVAY SA (BE) 2012-03-01 WO disclosed
EP-2282358-A1 Host material for light-emitting devices Solvay SA (BE) 2011-02-09 EP disclosed
EP-2282358-A1 Host material for light-emitting devices Solvay SA (BE) 2011-02-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10644243-B2 N-phenyl triscarbazole RB1, LBR, NR1I2 ATM 2980/4885KDM4E 1474/4885L3MBTL1 977/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.