Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 13/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | NPY4R | P50391 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | CCKAR | P32238 | 2/20 | 0.46 |
| ▸ | CCKBR | P32239 | 2/20 | 0.46 |
| ▸ | APC | P25054 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16486435 | 0.90 | NAALAD2 (0.68) | NAALAD2NPY1RNPY2RNPY4RACE | |
| SCHEMBL29854480 | 0.90 | NAALAD2 (0.68) | NAALAD2NPY1RNPY2RNPY4RACE | |
| SCHEMBL16486437 | 0.90 | NAALAD2 (0.68) | NAALAD2NPY1RNPY2RNPY4RACE | |
| SCHEMBL29854515 | 0.90 | NAALAD2 (0.68) | NAALAD2NPY1RNPY2RNPY4RACE | |
| SCHEMBL30584641 | 0.90 | OPRD1 (0.55) | NAALAD2OPRD1OPRM1OPRK1CCKAR | |
| SCHEMBL31031528 | 0.89 | NAALAD2 (0.55) | NAALAD2OPRD1OPRM1OPRK1 | |
| SCHEMBL159463 | 0.89 | NAALAD2 (0.69) | NAALAD2NPY1RNPY2RNPY4RACE | |
| SCHEMBL27412431 | 0.89 | NAALAD2 (0.69) | NAALAD2NPY1RNPY2RNPY4RACE | |
| SCHEMBL159464 | 0.89 | NAALAD2 (0.69) | NAALAD2NPY1RNPY2RNPY4RACE | |
| SCHEMBL31644345 | 0.89 | OPRD1 (0.57) | NAALAD2OPRD1OPRM1OPRK1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220165361-A1 | METHODS OF DIAGNOSING DISEASE | 4D Pharma Cork Limited (IE) | 2022-05-26 | — | — | US | claimed |
| CN-114127317-A | Method of diagnosing disease | 4D制药科克有限公司 | 2022-03-01 | — | — | CN | claimed |
| EP-3947744-A1 | METHODS OF DIAGNOSING DISEASE | 4D Pharma Cork Limited (IE) | 2022-02-09 | — | — | EP | claimed |
| US-20220165361-A1 | METHODS OF DIAGNOSING DISEASE | 4D Pharma Cork Limited (IE) | 2022-05-26 | — | — | US | disclosed |
| US-20220128556-A1 | METHODS OF DIAGNOSING DISEASE | 4D Pharma Cork Limited (IE) | 2022-04-28 | — | — | US | disclosed |
| CN-114127317-A | Method of diagnosing disease | 4D制药科克有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114040986-A | Method of diagnosing disease | 4D制药科克有限公司 | 2022-02-11 | — | — | CN | disclosed |
| EP-3947743-A1 | METHODS OF DIAGNOSING DISEASE | 4D Pharma Cork Limited (IE) | 2022-02-09 | — | — | EP | disclosed |
| EP-3947744-A1 | METHODS OF DIAGNOSING DISEASE | 4D Pharma Cork Limited (IE) | 2022-02-09 | — | — | EP | disclosed |