Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 12/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30552957 | 0.94 | ALDH1A1 (0.47) | OPRD1OPRM1OPRK1ALDH1A1LMNA | |
| SCHEMBL30585205 | 0.86 | ALDH1A1 (0.46) | OPRD1OPRM1OPRK1ALDH1A1LMNA | |
| SCHEMBL30585204 | 0.86 | ALDH1A1 (0.46) | OPRD1OPRM1OPRK1ALDH1A1LMNA | |
| SCHEMBL30585206 | 0.86 | ALDH1A1 (0.46) | OPRD1OPRM1OPRK1ALDH1A1LMNA | |
| SCHEMBL5173973 | 0.85 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL29385408 | 0.85 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL29385929 | 0.85 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL7746290 | 0.85 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL10791516 | 0.85 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTPTGS2TDP1 | |
| SCHEMBL29385198 | 0.85 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTPTGS2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240043943-A1 | METHODS AND COMPOSITIONS FOR PROTEASE REPORTER ASSAYS AND MODULATORS | 712 NORTH INC (US) | 2024-02-08 | — | — | US | disclosed |
| US-20240011070-A1 | METHODS AND COMPOSITIONS FOR PROTEASE REPORTER ASSAYS AND MODULATORS | 712 NORTH INC. (US) | 2024-01-11 | — | — | US | disclosed |
| EP-4192488-A2 | METHODS AND COMPOSITIONS FOR PROTEASE REPORTER ASSAYS AND MODULATORS | 712 North, Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022031476-A2 | METHODS AND COMPOSITIONS FOR PROTEASE REPORTER ASSAYS AND MODULATORS | 712 NORTH, INC. (US) | 2022-02-10 | — | — | WO | disclosed |