SCHEMBL29379909

SCHEMBL29379909

N=C(N)NCCC[C@H](N)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 15/20 0.56
▸ NPY1R P25929 9/20 0.56
▸ NPY5R Q15761 8/20 0.56
▸ NPY2R P49146 5/20 0.56
▸ ENPEP Q07075 3/20 0.48
▸ OPRM1 P35372 1/20 0.46
▸ OPRD1 P41143 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30335016 0.94 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2RENPEP
SCHEMBL29869065 0.93 NPY4R (0.48) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL29407334 0.93 NPY4R (0.48) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL30474555 0.93 NPY4R (0.57) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL29429181 0.90 NPY4R (0.59) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30411494 0.90 NPY4R (0.59) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29374790 0.90 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2ROPRM1
SCHEMBL31458901 0.90 NPY4R (0.53) NPY4RNPY1RNPY5RNPY2ROPRD1
SCHEMBL30668288 0.89 NPY4R (0.67) NPY4RNPY1RNPY5RNPY2RENPEP
SCHEMBL29374559 0.89 PTGS1 (0.43) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120053651-A Application of one-carbon metabolism inhibitor in preparation of medicine for treating toxic diffuse goiter 上海市第一人民医院 2025-05-30 — — CN disclosed
CN-119923278-A Dendrimer compositions for targeted delivery of fantasy therapeutic agents 约翰霍普金斯大学 2025-05-02 — — CN disclosed
US-20250114484-A1 ULTRASMALL NANOPARTICLES AND METHODS OF MAKING AND USING SAME UNIV CORNELL (US) 2025-04-10 — — US disclosed
CN-119789874-A Cannabis for targeted delivery vegetable dendrimer composition 约翰霍普金斯大学 2025-04-08 — — CN disclosed
US-12228553-B2 Ultrasmall nanoparticles and methods of making, using and analyzing same CORNELL UNIVERSITY (US) 2025-02-18 — — US disclosed
US-20250009894-A1 DENDRIMER COMPOSITIONS AND METHODS FOR TREATMENT OF SEVERE ACUTE RESPIRATORY DISTRESS SYNDROME Ashvattha Therapeutics, Inc. (US) 2025-01-09 — — US disclosed
US-12161734-B2 Multimodal silica-based nanoparticles SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2024-12-10 — — US disclosed
CN-118903483-A Nuclide internal irradiation treatment sensitization medicine and preparation method thereof 华中科技大学同济医学院附属协和医院 2024-11-08 — — CN disclosed
US-12115231-B2 Ultrasmall nanoparticles and methods of making and using same CORNELL UNIVERSITY (US) 2024-10-15 — — US disclosed
CN-107835696-B Subminiature nanoparticles and methods of making and using the same 康奈尔大学 2024-06-04 — — CN disclosed
CN-116410465-A Acid-responsive block copolymer, responsive micelle, preparation method and application thereof 国家纳米科学中心 2023-07-11 — — CN disclosed
US-20230140770-A1 ULTRASMALL NANOPARTICLES AND METHODS OF MAKING AND USING SAME CORNELL UNIVERSITY 2023-05-04 — — US disclosed
CN-115350285-A Selective delivery of dendrimers to brain tumors 约翰霍普金斯大学 2022-11-18 — — CN disclosed
CN-114948935-A Gallic acid derivative nano-drug, preparation method and application 厦门大学 2022-08-30 — — CN disclosed
US-11419955-B2 Multimodal silica-based nanoparticles SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2022-08-23 — — US disclosed
EP-2968621-B1 MULTIMODAL SILICA-BASED NANOPARTICLES MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-08-10 — — EP disclosed
CN-114652843-A Medicine for treating eye neovascularization, preparation method and application 厦门大学 2022-06-24 — — CN disclosed
CN-114392360-A Dendrimer compositions and use in the treatment of neurological and CNS disorders 约翰霍普金斯大学 2022-04-26 — — CN disclosed
US-11291737-B2 Ultrasmall nanoparticles and methods of making and using same CORNELL UNIVERSITY (US) 2022-04-05 — — US disclosed
CN-112773777-B cRGD-DFX-BSA-NPS nano particle and preparation method and application thereof 中国科学院长春应用化学研究所 2022-02-11 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250009894-A1 DENDRIMER COMPOSITIONS AND METHODS FOR TREATMENT OF SEVERE ACUTE RESPIRATORY DISTRESS SYNDROME TLR9, TLR3, ALB NPY4R 4650/4885NPY1R 4537/4885NPY5R 4398/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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