Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 8/20 | 0.48 |
| ▸ | NPY1R | P25929 | 5/20 | 0.48 |
| ▸ | NPY2R | P49146 | 4/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | FNTA | P49354 | 3/20 | 0.46 |
| ▸ | FNTB | P49356 | 3/20 | 0.46 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29869065 | 1.00 | NPY4R (0.48) | NPY4RNPY1RNPY2RNPY5RKEAP1 | |
| SCHEMBL29865541 | 0.94 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5RKEAP1 | |
| SCHEMBL31637483 | 0.94 | NPY4R (0.49) | NPY4RNPY1RNPY2RNPY5RKEAP1 | |
| SCHEMBL29379909 | 0.93 | NPY4R (0.56) | NPY4RNPY1RNPY2RNPY5ROPRM1 | |
| SCHEMBL30474503 | 0.92 | KEAP1 (0.52) | NPY4RNPY1RNPY2RNPY5RKEAP1 | |
| SCHEMBL31095858 | 0.92 | IL23R (0.48) | NPY4RNPY1RNPY2RNPY5RKEAP1 | |
| SCHEMBL29374250 | 0.92 | IL23R (0.48) | NPY4RNPY1RNPY2RNPY5RKEAP1 | |
| SCHEMBL31181298 | 0.92 | IL23R (0.52) | NPY4RNPY1RNPY2RNPY5RKEAP1 | |
| SCHEMBL30264901 | 0.91 | FNTA (0.52) | NPY4RNPY1RNPY2RNPY5ROPRM1 | |
| SCHEMBL29374559 | 0.90 | PTGS1 (0.43) | NPY4RNPY1RNPY2RNPY5RKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119923278-A | Dendrimer compositions for targeted delivery of fantasy therapeutic agents | 约翰霍普金斯大学 | 2025-05-02 | — | — | CN | disclosed |
| CN-119789874-A | Cannabis for targeted delivery vegetable dendrimer composition | 约翰霍普金斯大学 | 2025-04-08 | — | — | CN | disclosed |
| CN-119033696-A | Ultra-small-size CeO2Gd@BSA-cRGD targeted nanoparticle and green preparation method thereof | 哈尔滨医科大学 | 2024-11-29 | — | — | CN | disclosed |
| CN-118903483-A | Nuclide internal irradiation treatment sensitization medicine and preparation method thereof | 华中科技大学同济医学院附属协和医院 | 2024-11-08 | — | — | CN | disclosed |
| CN-118792246-A | Shell-vesicle hydrogel based on liquid-liquid phase separation | 济南微生态生物医学省实验室 | 2024-10-18 | — | — | CN | disclosed |
| CN-113874728-B | Bioelectronic circuits, systems, and methods of making and using the same | 代表亚利桑那大学的亚利桑那校董事会 | 2024-09-17 | — | — | CN | disclosed |
| CN-118043076-A | Dendrimer conjugates of small molecule biologicals for intracellular delivery | 约翰霍普金斯大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-108430514-B | Compositions and methods for treating peroxisome disorders and leukodystrophies | 约翰霍普金斯大学 | 2023-11-03 | — | — | CN | disclosed |
| CN-115433357-B | Macromolecular indoleamine 2, 3-dioxygenase inhibitor based on polyamino acid, and preparation method and application thereof | 苏州大学 | 2023-10-10 | — | — | CN | disclosed |
| CN-111867633-B | Covalent anesthetic-polymer conjugates for achieving prolonged local anesthesia | 儿童医学中心公司 | 2023-09-22 | — | — | CN | disclosed |
| CN-116410465-A | Acid-responsive block copolymer, responsive micelle, preparation method and application thereof | 国家纳米科学中心 | 2023-07-11 | — | — | CN | disclosed |
| CN-116056729-A | Method for degrading endogenous proteins | 南卡罗莱纳大学 | 2023-05-02 | — | — | CN | disclosed |
| US-20230016609-A1 | MESOPOROUS SILICA NANOPARTICLES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-01-19 | — | — | US | disclosed |
| WO-2022253342-A1 | SMALL MICELLE NANO-DRUG, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州大学 | 2022-12-08 | — | — | WO | disclosed |
| CN-115433357-A | Macromolecular indoleamine 2, 3-dioxygenase inhibitor based on polyamino acid and preparation method and application thereof | 苏州大学 | 2022-12-06 | — | — | CN | disclosed |
| CN-115350285-A | Selective delivery of dendrimers to brain tumors | 约翰霍普金斯大学 | 2022-11-18 | — | — | CN | disclosed |
| CN-114392360-A | Dendrimer compositions and use in the treatment of neurological and CNS disorders | 约翰霍普金斯大学 | 2022-04-26 | — | — | CN | disclosed |
| US-11260127-B2 | Mesoporous silica nanoparticles for diagnostic and therapeutic applications | CASE WESTERN RESERVE UNIVERSITY (US) | 2022-03-01 | — | — | US | disclosed |