Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4554003 | 0.96 | USP30 (0.49) | USP30GPR119EPHX1EPHX2KCNH2 | |
| SCHEMBL2936390 | 0.87 | GPR119 (0.62) | GPR119 | |
| SCHEMBL2936389 | 0.87 | GPR119 (0.62) | GPR119 | |
| SCHEMBL2930818 | 0.85 | GPR119 (0.46) | USP30GPR119EPHX1EPHX2KCNH2 | |
| SCHEMBL2938422 | 0.85 | USP30 (0.44) | USP30GPR119EPHX1EPHX2KCNH2 | |
| SCHEMBL2938418 | 0.85 | USP30 (0.44) | USP30GPR119EPHX1EPHX2KCNH2 | |
| SCHEMBL2930817 | 0.85 | GPR119 (0.46) | USP30GPR119EPHX1EPHX2KCNH2 | |
| SCHEMBL2939940 | 0.85 | GPR119 (0.50) | USP30GPR119EPHX1EPHX2KCNH2 | |
| SCHEMBL2937898 | 0.84 | USP30 (0.44) | USP30GPR119EPHX1EPHX2KCNH2 | |
| SCHEMBL2937900 | 0.83 | GPR119 (0.62) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134704-B1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2010-09-22 | — | — | EP | claimed |