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Sugi Predict / Compounds / SCHEMBL29382235

SCHEMBL29382235

SCHEMBL29382235

C[C@H](N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)NCC(=O)O)[C@@H](C)O

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 17/20 0.50
▸ SCTR P47872 1/20 0.49
▸ KEAP1 Q14145 1/20 0.47
▸ OPRL1 P41146 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30475874 0.86 NPY4R (0.49) —
SCHEMBL7447502 0.86 GLP1R (0.53) GLP1RSCTRKEAP1
SCHEMBL7447496 0.86 GLP1R (0.53) GLP1RSCTRKEAP1
SCHEMBL30150658 0.85 GLP1R (0.49) GLP1RKEAP1
SCHEMBL31683313 0.84 IL23R (0.59) GLP1RSCTR
SCHEMBL11574527 0.84 GLP1R (0.63) GLP1RSCTRKEAP1
SCHEMBL11578343 0.84 GLP1R (0.63) GLP1RSCTRKEAP1
SCHEMBL29387939 0.83 PTPN1 (0.48) GLP1RSCTRKEAP1
SCHEMBL30512618 0.83 GLP1R (0.56) GLP1RSCTR
SCHEMBL30883272 0.83 TFPI (0.56) GLP1RSCTROPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240043943-A1 METHODS AND COMPOSITIONS FOR PROTEASE REPORTER ASSAYS AND MODULATORS 712 NORTH INC (US) 2024-02-08 — — US disclosed
US-20240011070-A1 METHODS AND COMPOSITIONS FOR PROTEASE REPORTER ASSAYS AND MODULATORS 712 NORTH INC. (US) 2024-01-11 — — US disclosed
CN-117241819-A Methods and compositions for protease reporter gene detection methods and protease reporter gene modulators 712北方公司 2023-12-15 — — CN disclosed
EP-4192488-A2 METHODS AND COMPOSITIONS FOR PROTEASE REPORTER ASSAYS AND MODULATORS 712 North, Inc. (US) 2023-06-14 — — EP disclosed
WO-2022031476-A2 METHODS AND COMPOSITIONS FOR PROTEASE REPORTER ASSAYS AND MODULATORS 712 NORTH, INC. (US) 2022-02-10 — — WO disclosed
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