Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | BACE1 | P56817 | 3/20 | 0.47 |
| ▸ | GLP1R | P43220 | 4/20 | 0.47 |
| ▸ | SCTR | P47872 | 1/20 | 0.47 |
| ▸ | VIPR2 | P41587 | 4/20 | 0.45 |
| ▸ | VIPR1 | P32241 | 2/20 | 0.45 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.45 |
| ▸ | NPY1R | P25929 | 2/20 | 0.45 |
| ▸ | NPY4R | P50391 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | CTSH | P09668 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29840375 | 0.97 | GLP1R (0.47) | PTPN1BACE1GLP1RSCTRVIPR2 | |
| SCHEMBL29476637 | 0.94 | NPY4R (0.45) | PTPN1BACE1GLP1RSCTRNPY5R | |
| SCHEMBL29519643 | 0.94 | BACE1 (0.49) | BACE1GLP1RSCTRNPY5RNPY1R | |
| SCHEMBL29889146 | 0.93 | NPY4R (0.46) | GLP1RSCTRNPY5RNPY1RNPY4R | |
| SCHEMBL30956347 | 0.92 | GLP1R (0.51) | BACE1GLP1RSCTRVIPR2VIPR1 | |
| SCHEMBL30475882 | 0.91 | NPY4R (0.49) | PTPN1GLP1RSCTRNPY5RNPY1R | |
| SCHEMBL30956352 | 0.91 | GLP1R (0.53) | GLP1RSCTRKEAP1 | |
| SCHEMBL30475873 | 0.90 | NPY4R (0.45) | GLP1RSCTRNPY5RNPY1RNPY4R | |
| SCHEMBL29482469 | 0.90 | NPY4R (0.45) | GLP1RSCTRNPY5RNPY1RNPY4R | |
| SCHEMBL30252503 | 0.90 | NPY4R (0.54) | BACE1NPY5RNPY1RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220047605-A1 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | SOLENO THERAPEUTICS, INC. | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220047605-A1 | SALTS OF POTASSIUM ATP CHANNEL OPENERS AND USES THEREOF | KCNJ1, KCNJ11, KCNJ2 | PTPN1 3092/4885BACE1 1975/4885GLP1R 337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.