SCHEMBL2938428

SCHEMBL2938428

CCCCCCCCc1ccc(O)c(-c2cc(CCCCCCCC)ccc2O)c1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.71
CNR2 P34972 1/20 0.71
KAT8 Q9H7Z6 2/20 0.63
PTGS2 P35354 3/20 0.60
ESR1 P03372 2/20 0.60
ADRA2A P08913 2/20 0.60
ADORA3 P0DMS8 2/20 0.60
TACR2 P21452 2/20 0.60
SLC6A2 P23975 2/20 0.60
SLC6A4 P31645 2/20 0.60
SLC6A3 Q01959 2/20 0.60
KDM4E B2RXH2 1/20 0.60
ALDH1A1 P00352 1/20 0.60
LMNA P02545 1/20 0.60
SHBG P04278 1/20 0.60
TP53 P04637 1/20 0.60
CYP3A4 P08684 1/20 0.60
HSPD1 P10809 1/20 0.60
ADRB3 P13945 1/20 0.60
HTR2C P28335 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL723543 0.92 CNR1 (0.77) CNR1CNR2KAT8PTGS2ESR1
SCHEMBL9625122 0.92 CNR1 (0.61) CNR1CNR2KAT8PTGS2ESR1
SCHEMBL8940890 0.87 GABRA1 (0.57) CNR1CNR2KAT8CYP3A4PPARA
SCHEMBL27976452 0.87 BACE1 (0.62) CNR1CNR2KAT8PTGS2ESR1
SCHEMBL4373486 0.87 BACE1 (0.62) CNR1CNR2KAT8PTGS2ESR1
SCHEMBL28097794 0.87 BACE1 (0.62) CNR1CNR2KAT8PTGS2ESR1
SCHEMBL2782711 0.86 IGF1R (0.76) KAT8PTGS2ESR1ADRA2AADORA3
SCHEMBL70343 0.86 IGF1R (0.76) KAT8PTGS2ESR1ADRA2AADORA3
SCHEMBL11721061 0.86 IGF1R (0.76) KAT8PTGS2ESR1ADRA2AADORA3
SCHEMBL11616856 0.86 IGF1R (0.76) KAT8PTGS2ESR1ADRA2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1411086-B1 THERMOPLASTIC POLYMER COMPOSITION KURARAY CO (JP) 2010-09-15 EP disclosed
EP-1411083-B1 VINYL CHLORIDE POLYMER COMPOSITION KURARAY CO (JP) 2008-06-18 EP disclosed
US-7138447-B2 Thermoplastic polymer composition KURARAY CO., LTD. (JP) 2006-11-21 US disclosed
US-7138175-B2 Thermoplastic polymer composition KURARAY CO., LTD. (JP) 2006-11-21 US disclosed
US-7041735-B2 Vinyl chloride polymer composition KURARAY CO., LTD. (JP) 2006-05-09 US disclosed
US-20050261427-A1 Thermoplastic polymer composition KURARAY CO., LTD (JP) 2005-11-24 US disclosed
EP-1535964-A1 THERMOPLASTIC POLYMER COMPOSITION KURARAY CO., LTD. (JP) 2005-06-01 EP disclosed
US-20040176525-A1 Thermoplastic polymer composition KURARAY CO., LTD. (JP) 2004-09-09 US disclosed
US-20040171751-A1 Vinyl chloride polymer composition KURARAY CO., LTD. (JP) 2004-09-02 US disclosed
EP-1411086-A1 THERMOPLASTIC POLYMER COMPOSITION Kuraray Co., Ltd. (JP) 2004-04-21 EP disclosed
EP-1411083-A1 VINYL CHLORIDE POLYMER COMPOSITION KURARAY CO., LTD. (JP) 2004-04-21 EP disclosed