SCHEMBL29384669

SCHEMBL29384669

CCCn1c(=O)c2[nH]c(-c3cnn(CC#Cc4cccc(C(=O)O)c4)c3)nc2n2ccnc12

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ADORA2B P29275 20/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25420975 1.00 ADORA2B (0.79) ADORA2B
SCHEMBL23067591 0.92 ADORA2B (0.66) ADORA2B
SCHEMBL29758428 0.92 ADORA2B (0.66) ADORA2B
SCHEMBL21121491 0.91 ADORA2B (0.65) ADORA2B
SCHEMBL29384903 0.89 ADORA2B (0.78) ADORA2B
SCHEMBL1065212 0.88 ADORA2B (1.00) ADORA2B
SCHEMBL29386663 0.87 ADORA2B (0.79) ADORA2B
SCHEMBL21153172 0.86 ADORA2B (0.60) ADORA2B
SCHEMBL29387969 0.86 ADORA2B (0.60) ADORA2B
SCHEMBL4412468 0.86 ADORA2B (1.00) ADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4192916-A1 COMBINATION THERAPY WITH ADENOSINE RECEPTOR ANTAGONISTS Teon Therapeutics, Inc. (US) 2023-06-14 EP disclosed
WO-2022032091-A1 COMBINATION THERAPY WITH ADENOSINE RECEPTOR ANTAGONISTS TEON THERAPEUTICS, INC. (US) 2022-02-10 WO disclosed