SCHEMBL29385010

SCHEMBL29385010

COc1cc2c(NC3CCN(C)CC3)nc(N3CCCN(C)CC3)nc2cc1OCCCN1CCOCC1

nearest known ligand 0.88

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 20/20 0.88
EHMT1 Q9H9B1 5/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25243208 1.00 EHMT2 (0.88) EHMT2EHMT1
SCHEMBL25235013 0.94 EHMT2 (0.88) EHMT2EHMT1
SCHEMBL29382706 0.94 EHMT2 (0.88) EHMT2EHMT1
SCHEMBL29384966 0.94 EHMT2 (1.00) EHMT2EHMT1
SCHEMBL25208627 0.94 EHMT2 (1.00) EHMT2EHMT1
SCHEMBL25200166 0.93 EHMT2 (1.00) EHMT2EHMT1
SCHEMBL29382283 0.93 EHMT2 (1.00) EHMT2EHMT1
SCHEMBL25229558 0.91 EHMT2 (0.83) EHMT2EHMT1
SCHEMBL29382797 0.91 EHMT2 (0.83) EHMT2EHMT1
SCHEMBL25239670 0.89 EHMT2 (0.80) EHMT2EHMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4192826-A1 SMALL MOLECULES FOR THE TREATMENT OF AUTOIMMUNE DISEASES AND CANCER Athos Therapeutics, Inc. (US) 2023-06-14 EP disclosed
WO-2022031939-A1 SMALL MOLECULES FOR THE TREATMENT OF AUTOIMMUNE DISEASES AND CANCER ATHOS THERAPEUTICS, INC. (US) 2022-02-10 WO disclosed