SCHEMBL25200166

SCHEMBL25200166

COc1cc2c(NC3CCN(C)CC3)nc(N3CCCN(C)CC3)nc2cc1OCCCN1CCCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 20/20 1.00
CHD1 O14646 2/20 0.80
EHMT1 Q9H9B1 3/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29382283 1.00 EHMT2 (1.00) EHMT2CHD1EHMT1
SCHEMBL25208627 0.99 EHMT2 (1.00) EHMT2CHD1EHMT1
SCHEMBL29384966 0.99 EHMT2 (1.00) EHMT2CHD1EHMT1
SCHEMBL19617550 0.94 EHMT2 (0.98) EHMT2CHD1EHMT1
SCHEMBL25230546 0.94 EHMT2 (1.00) EHMT2CHD1
SCHEMBL29385494 0.94 EHMT2 (0.98) EHMT2CHD1EHMT1
SCHEMBL25204606 0.94 EHMT2 (1.00) EHMT2EHMT1
SCHEMBL29382539 0.94 EHMT2 (1.00) EHMT2EHMT1
SCHEMBL25204668 0.93 EHMT2 (1.00) EHMT2CHD1EHMT1
SCHEMBL25235013 0.93 EHMT2 (0.88) EHMT2CHD1EHMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4192826-A1 SMALL MOLECULES FOR THE TREATMENT OF AUTOIMMUNE DISEASES AND CANCER Athos Therapeutics, Inc. (US) 2023-06-14 EP disclosed
US-20230159498-A1 SMALL MOLECULES FOR THE TREATMENT OF AUTOIMMUNE DISEASES AND CANCER ATHOS THERAPEUTICS, INC. 2023-05-25 US disclosed
US-11485728-B2 Small molecules for the treatment of autoimmune diseases and cancer ATHOS THERAPEUTICS, INC. (US) 2022-11-01 US disclosed
US-20220073498-A1 SMALL MOLECULES FOR THE TREATMENT OF AUTOIMMUNE DISEASES AND CANCER ATHOS THERAPEUTICS, INC. 2022-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159498-A1 SMALL MOLECULES FOR THE TREATMENT OF AUTOIMMUNE DISEASES AND CANCER SSB, HLA-DRB1, UACA EHMT2 1523/4885CHD1 3110/4885EHMT1 1748/4885
US-11485728-B2 Small molecules for the treatment of autoimmune diseases and cancer SSB, HLA-DRB1, UACA EHMT2 1523/4885CHD1 3110/4885EHMT1 1748/4885
US-20220073498-A1 SMALL MOLECULES FOR THE TREATMENT OF AUTOIMMUNE DISEASES AND CANCER SSB, HLA-DRB1, UACA EHMT2 1523/4885CHD1 3110/4885EHMT1 1748/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.