Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 8/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 7/20 | 0.58 |
| ▸ | PRKCD | Q05655 | 6/20 | 0.58 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.58 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.58 |
| ▸ | PRKD2 | Q9BZL6 | 3/20 | 0.58 |
| ▸ | PLK4 | O00444 | 2/20 | 0.58 |
| ▸ | MARK3 | P27448 | 2/20 | 0.58 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.58 |
| ▸ | MARK2 | Q7KZI7 | 2/20 | 0.58 |
| ▸ | NQO2 | P16083 | 2/20 | 0.58 |
| ▸ | CDK9 | P50750 | 2/20 | 0.58 |
| ▸ | PKN1 | Q16512 | 2/20 | 0.58 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.58 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.58 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.58 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.58 |
| ▸ | PRKACA | P17612 | 5/20 | 0.57 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.57 |
| ▸ | PRKACG | P22612 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23795402 | 0.87 | PRKCD (0.57) | ROCK1ROCK2PRKCDPKN2AURKB | |
| SCHEMBL30439459 | 0.87 | PRKCD (0.57) | ROCK1ROCK2PRKCDPKN2AURKB | |
| SCHEMBL30439363 | 0.87 | PRKCD (0.57) | ROCK1ROCK2PRKCDPKN2AURKB | |
| SCHEMBL23795296 | 0.87 | PRKCD (0.57) | ROCK1ROCK2PRKCDPKN2AURKB | |
| SCHEMBL19350236 | 0.87 | PRKCD (0.57) | ROCK1ROCK2PRKCDPKN2AURKB | |
| Hydrochloric Acid SCHEMBL23795390 | 0.86 | PRKCD (0.58) | ROCK1ROCK2PRKCDPKN2AURKB | |
| Hydrochloric Acid SCHEMBL23795335 | 0.86 | PRKCD (0.58) | ROCK1ROCK2PRKCDPKN2AURKB | |
| Hydrochloric Acid SCHEMBL30439323 | 0.86 | PRKCD (0.58) | ROCK1ROCK2PRKCDPKN2AURKB | |
| Hydrochloric Acid SCHEMBL30438942 | 0.86 | PRKCD (0.58) | ROCK1ROCK2PRKCDPKN2AURKB | |
| SCHEMBL23795417 | 0.85 | PRKCD (0.55) | ROCK1ROCK2PRKCDPKN2AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260124250-A1 | METHODS FOR SELECTING CULTURED CORNEAL ENDOTHELIAL CELLS | UNIV MAASTRICHT (NL) | 2026-05-07 | — | — | US | disclosed |
| EP-4655392-A2 | METHODS FOR SELECTING CULTURED CORNEAL ENDOTHELIAL CELLS | Universiteit Maastricht (NL) | 2025-12-03 | — | — | EP | disclosed |
| WO-2024158290-A2 | METHODS FOR SELECTING CULTURED CORNEAL ENDOTHELIAL CELLS | UNIVERSITEIT MAASTRICHT (NL) | 2024-08-02 | — | — | WO | disclosed |
| WO-2022025239-A1 | METHOD FOR ENHANCING THERAPEUTIC EFFECT OF CORNEAL ENDOTHELIAL CELL INJECTION THERAPY | 学校法人同志社 | 2022-02-03 | — | — | WO | disclosed |
| WO-2022025240-A1 | METHOD AND VESSEL FOR PRESERVING CORNEAL ENDOTHELIAL CELLS | 学校法人同志社 | 2022-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260124250-A1 | METHODS FOR SELECTING CULTURED CORNEAL ENDOTHELIAL CELLS | TAGLN2, CNN2, TMIGD3 | ROCK1 810/4885ROCK2 580/4885PRKCD 2455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.