Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCD | Q05655 | 6/20 | 0.57 |
| ▸ | PRKACA | P17612 | 5/20 | 0.57 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.57 |
| ▸ | PRKACG | P22612 | 4/20 | 0.57 |
| ▸ | PRKACB | P22694 | 4/20 | 0.57 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.57 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.57 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.57 |
| ▸ | PRKCG | P05129 | 3/20 | 0.57 |
| ▸ | PRKCB | P05771 | 3/20 | 0.57 |
| ▸ | PRKCA | P17252 | 3/20 | 0.57 |
| ▸ | PRKCH | P24723 | 3/20 | 0.57 |
| ▸ | PRKCI | P41743 | 3/20 | 0.57 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23795402 | 1.00 | PRKCD (0.57) | PRKCDPRKACAPRKD3PRKACGPRKACB | |
| SCHEMBL23795296 | 1.00 | PRKCD (0.57) | PRKCDPRKACAPRKD3PRKACGPRKACB | |
| SCHEMBL30439459 | 1.00 | PRKCD (0.57) | PRKCDPRKACAPRKD3PRKACGPRKACB | |
| Hydrochloric Acid SCHEMBL23795335 | 0.99 | PRKCD (0.58) | PRKCDPRKACAPRKD3PRKACGPRKACB | |
| Hydrochloric Acid SCHEMBL23795390 | 0.99 | PRKCD (0.58) | PRKCDPRKACAPRKD3PRKACGPRKACB | |
| Hydrochloric Acid SCHEMBL30439323 | 0.99 | PRKCD (0.58) | PRKCDPRKACAPRKD3PRKACGPRKACB | |
| Hydrochloric Acid SCHEMBL30438942 | 0.99 | PRKCD (0.58) | PRKCDPRKACAPRKD3PRKACGPRKACB | |
| SCHEMBL13513879 | 0.94 | PRKCD (0.65) | PRKCDPRKACAPRKD3PRKACGPRKACB | |
| SCHEMBL19350236 | 0.87 | PRKCD (0.57) | PRKCDPRKACAPRKD3PRKACGPRKACB | |
| SCHEMBL29385240 | 0.87 | ROCK1 (0.58) | PRKCDPRKACAPRKD3PRKACGPRKACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116555-B | Rho kinase inhibitor and preparation method and application thereof | 北京盈科瑞创新药物研究有限公司 | 2023-06-02 | — | — | CN | claimed |
| CN-111116555-B | Rho kinase inhibitor and preparation method and application thereof | 北京盈科瑞创新药物研究有限公司 | 2023-06-02 | — | — | CN | disclosed |