Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438525 | 0.87 | MEN1 (0.43) | MEN1KMT2ALMNANPSR1ADORA1 | |
| SCHEMBL31562050 | 0.87 | MEN1 (0.43) | MEN1KMT2ALMNANPSR1ADORA1 | |
| SCHEMBL8438521 | 0.87 | MEN1 (0.43) | MEN1KMT2ALMNANPSR1ADORA1 | |
| SCHEMBL20002160 | 0.80 | KMT2A (0.56) | MEN1KMT2ALMNANPSR1SMN1; SMN2 | |
| SCHEMBL17358752 | 0.79 | HSD17B10 (0.41) | MEN1KMT2ALMNANPSR1SMN1; SMN2 | |
| SCHEMBL4869226 | 0.79 | HSD17B10 (0.47) | LMNANPSR1ADORA1SMN1; SMN2NPC1 | |
| SCHEMBL15606327 | 0.79 | HSD17B10 (0.47) | LMNANPSR1ADORA1SMN1; SMN2NPC1 | |
| SCHEMBL8235326 | 0.79 | HSD17B10 (0.41) | MEN1KMT2ALMNANPSR1SMN1; SMN2 | |
| SCHEMBL10215478 | 0.79 | NPC1 (0.41) | LMNANPSR1SMN1; SMN2NPC1HSD17B10 | |
| SCHEMBL4547486 | 0.79 | HSD17B10 (0.47) | LMNANPSR1ADORA1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057739-A | Diazepinone derivatives and their use in the treatment of hepatitis b infections | 诺维拉治疗公司 | 2022-02-18 | — | — | CN | disclosed |