SCHEMBL29385708

SCHEMBL29385708

CC(C)c1cc(-c2ccc(F)c3ccccc23)nc(N)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 1/20 1.00
HTR2B P41595 1/20 1.00
GPR65 Q8IYL9 1/20 1.00
AURKA O14965 1/20 0.44
PDPK1 O15530 1/20 0.44
TGFBR1 P36897 1/20 0.44
AURKB Q96GD4 1/20 0.44
CDK1 P06493 1/20 0.42
CDK2 P24941 1/20 0.42
HSP90AA1 P07900 6/20 0.38
HSP90AB1 P08238 4/20 0.38
FEN1 P39748 4/20 0.37
ALOX5AP P20292 3/20 0.37
ADORA2A P29274 2/20 0.36
MAPK14 Q16539 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
ADORA1 P30542 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29391421 1.00 HTR1B (1.00) HTR1BHTR2BGPR65AURKAPDPK1
SCHEMBL375979 1.00 HTR1B (1.00) HTR1BHTR2BGPR65AURKAPDPK1
Hydrochloric Acid SCHEMBL5746097 0.99 HTR1B (0.97) HTR1BHTR2BGPR65AURKAPDPK1
SCHEMBL8469545 0.99 HTR1B (0.97) HTR1BHTR2BGPR65AURKAPDPK1
SCHEMBL5749142 0.91 HTR1B (0.84) HTR1BHTR2BGPR65AURKAPDPK1
Fumaric Acid SCHEMBL5773986 0.89 HTR1B (0.80) HTR1BHTR2BGPR65AURKAPDPK1
Maleic Acid SCHEMBL5773984 0.89 HTR1B (0.80) HTR1BHTR2BGPR65AURKAPDPK1
SCHEMBL5749044 0.88 HTR1B (0.78) HTR1BHTR2BGPR65AURKAPDPK1
SCHEMBL5749623 0.88 HTR1B (0.78) HTR1BHTR2BGPR65AURKAPDPK1
Hydrochloric Acid SCHEMBL5748497 0.85 HTR1B (0.74) HTR1BHTR2BGPR65AURKAPDPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119614365-A Continuous flow magnetic field biological fermentation and catalytic synthesis device and method 英都斯特(无锡)感应科技有限公司 2025-03-14 CN claimed
CN-119549671-A Electromagnetic treatment equipment and method for continuous casting and rolling of aluminum alloy 内蒙古冶科电磁能科技有限公司 2025-03-04 CN claimed
US-20240408071-A1 NOVEL COMBINATION OF SEROTONIN RECEPTOR (5-HTR2B) ANTAGONIST AND AN IMMUNOMODULATOR AND CHEMOTHERAPEUTIC DRUGS FOR INHIBITION OF CANCER NATIONAL CENTRE FOR CELL SCIENCE (IN) 2024-12-12 US claimed
EP-4408397-A1 NOVEL COMBINATION OF SEROTONIN RECEPTOR (5-HTR) ANTAGONIST AND AN IMMUNOMODULATOR AND CHEMOTHERAPEUTIC DRUGS FOR INHIBITION OF CANCER National Centre For Cell Science (IN) 2024-08-07 EP claimed
CN-118080354-A Novel roll grinding-dry grading-air flow suspension dry sorting method for iron-containing surrounding rock 包钢集团矿山研究院(有限责任公司) 2024-05-28 CN claimed
CN-118080163-A Airflow suspension dry magnetic separation combined system suitable for recycling magnetic iron in iron-containing surrounding rock 包钢集团矿山研究院(有限责任公司) 2024-05-28 CN claimed
CN-118047504-A Enhanced Fenton process for treating dimethyl sulfoxide-containing wastewater 中复神鹰碳纤维股份有限公司 2024-05-17 CN claimed
CN-117672913-A Process chamber, warming method thereof, semiconductor device and storage medium 北京北方华创微电子装备有限公司 2024-03-08 CN claimed
CN-114807462-B Method for hot rolling sludge by utilizing steel slag hot-disintegrating treatment 马鞍山钢铁股份有限公司 2023-09-22 CN claimed
WO-2023053142-A1 NOVEL COMBINATION OF SEROTONIN RECEPTOR (5-HTR2B) ANTAGONIST AND AN IMMUNOMODULATOR AND CHEMOTHERAPEUTIC DRUGS FOR INHIBITION OF CANCER NATIONAL CENTRE FOR CELL SCIENCE (IN) 2023-04-06 WO claimed
CN-115677500-A Method for promoting high-efficiency synthesis of perfluoroketo ester by magnetically driving micro rotor 扬州大学 2023-02-03 CN claimed
CN-114807462-A Method for hot-rolling oil sludge through hot-disintegration treatment of steel slag 马鞍山钢铁股份有限公司 2022-07-29 CN claimed
CN-115241034-B Semiconductor processing method and semiconductor processing equipment 北京北方华创微电子装备有限公司 2026-05-12 CN disclosed
US-12622234-B2 Selective in-situ carbon-based mask protection TOKYO ELECTRON LIMITED (JP) 2026-05-05 US disclosed
US-20260085210-A1 MULTILAYER COATING SYSTEMS OBTAINED FROM BLOCK COPOLYMER CONTAINING BASECOAT COMPOSITIONS BASF COATINGS GMBH (DE) 2026-03-26 US disclosed
US-20260053831-A1 COMPOSITIONS AND METHODS FOR IMPROVING COGNITIVE FUNCTION DIAMOND THERAPEUTICS INC (CA) 2026-02-26 US disclosed
US-11274158-B2 Methods and compositions for treating inflammatory or autoimmune diseases or conditions using calcitonin receptor activators FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2022-03-15 US disclosed
CN-110923707-B Titanium alloy surface high-temperature-resistant composite coating material based on laser cladding 中北大学 2022-03-11 CN disclosed
CN-114121798-A Semiconductor structure and forming method thereof 中芯国际集成电路制造(上海)有限公司 2022-03-01 CN disclosed
CN-114040767-A Methods and compositions comprising 5HT receptor agonists for the treatment of psychological, cognitive, behavioral and/or emotional disorders 钻石治疗公司 2022-02-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622234-B2 Selective in-situ carbon-based mask protection CDH1, EPCAM, C9 HTR1B 3756/4885HTR2B 3146/4885GPR65 3020/4885
US-20260085210-A1 MULTILAYER COATING SYSTEMS OBTAINED FROM BLOCK COPOLYMER CONTAINING BASECOAT COMPOSITIONS B2M, PBRM1, F13B HTR1B 1200/4885HTR2B 736/4885GPR65 2994/4885
US-20260053831-A1 COMPOSITIONS AND METHODS FOR IMPROVING COGNITIVE FUNCTION HTR1B, HTR2B, HTR3B HTR1B 1/4885HTR2B 2/4885GPR65 104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.