Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC5 | O15392 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | PRKACG | P22612 | 1/20 | 0.40 |
| ▸ | PRKACB | P22694 | 1/20 | 0.40 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28677436 | 1.00 | BIRC5 (0.41) | BIRC5PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL17072846 | 0.73 | PRKD3 (0.50) | BIRC5PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL29826705 | 0.73 | BIRC5 (0.47) | BIRC5PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL2187570 | 0.73 | BIRC5 (0.47) | BIRC5PRKD3PRKCGPRKCBPRKCA | |
| Methane SCHEMBL27922537 | 0.72 | BIRC5 (0.46) | BIRC5PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL23075523 | 0.69 | BIRC5 (0.47) | BIRC5PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL983397 | 0.69 | CDC7 (0.49) | BIRC5PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL5661417 | 0.69 | BIRC5 (0.47) | BIRC5PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL2410450 | 0.69 | TRAP1 (0.50) | BIRC5PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL31310579 | 0.69 | BIRC5 (0.47) | BIRC5PRKD3PRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114031613-A | 1- (benzo [ b ] thiophene-7-yl) -indole derivative and synthetic method thereof | 湖南第一师范学院 | 2022-02-11 | — | — | CN | claimed |
| CN-114031613-A | 1- (benzo [ b ] thiophene-7-yl) -indole derivative and synthetic method thereof | 湖南第一师范学院 | 2022-02-11 | — | — | CN | disclosed |
| CN-114031613-A | 1- (benzo [ b ] thiophene-7-yl) -indole derivative and synthetic method thereof | 湖南第一师范学院 | 2022-02-11 | — | — | CN | disclosed |
| CN-114031613-A | 1- (benzo [ b ] thiophene-7-yl) -indole derivative and synthetic method thereof | 湖南第一师范学院 | 2022-02-11 | — | — | CN | disclosed |