Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.41 |
| ▸ | KRAS | P01116 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26134377 | 0.75 | KRAS (0.45) | HTR6KAT6AKRASMEN1KMT2A | |
| SCHEMBL26134380 | 0.75 | KRAS (0.45) | HTR6KAT6AKRASMEN1KMT2A | |
| SCHEMBL28604190 | 0.74 | POLB (0.46) | KAT6ANFE2L2PKML3MBTL1SMN1; SMN2 | |
| SCHEMBL28587399 | 0.72 | MEN1 (0.53) | KAT6AMEN1KMT2ANFE2L2PKM | |
| SCHEMBL28591290 | 0.71 | PKM (0.63) | MEN1KMT2ANFE2L2PKML3MBTL1 | |
| SCHEMBL4186031 | 0.70 | ABCG2 (0.43) | HTR6KAT6AKMT2AABCG2PKM | |
| SCHEMBL4186035 | 0.70 | ABCG2 (0.43) | HTR6KAT6AKMT2AABCG2PKM | |
| SCHEMBL4186037 | 0.70 | ABCG2 (0.43) | HTR6KAT6AKMT2AABCG2PKM | |
| SCHEMBL28595097 | 0.70 | PKM (0.49) | HTR6MEN1KMT2APKML3MBTL1 | |
| SCHEMBL305745 | 0.70 | ERN1 (0.47) | KRASKMT2AABCG2NFE2L2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113061103-B | Preparation method of monofluoroolefin derivative | 中国科学院兰州化学物理研究所 | 2022-02-15 | — | — | CN | claimed |