Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 5/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 6/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14520683 | 0.86 | ESR2 (0.41) | RBP4ESR2ADORA1NR1H2EP300 | |
| SCHEMBL4792110 | 0.86 | ADORA1 (0.46) | RBP4ESR2ADORA1NR1H2EP300 | |
| SCHEMBL4795587 | 0.86 | NPC1 (0.48) | RBP4GAAMAPK1PARP1 | |
| SCHEMBL25430237 | 0.85 | ADORA1 (0.43) | RBP4ESR2ADORA1NR1H2EP300 | |
| SCHEMBL17870544 | 0.85 | RBP4 (0.40) | RBP4ESR2ADORA1NR1H2EP300 | |
| SCHEMBL17878107 | 0.84 | MAPK1 (0.42) | RBP4ESR2ADORA1NR1H2EP300 | |
| SCHEMBL5465401 | 0.84 | KDM4E (0.47) | RBP4GAANAMPT | |
| SCHEMBL22482006 | 0.83 | RBP4 (0.41) | RBP4EP300CREBBPGAABRD4 | |
| SCHEMBL22482203 | 0.83 | CDK5 (0.44) | RBP4GAANAMPT | |
| SCHEMBL17870541 | 0.82 | RBP4 (0.39) | RBP4ESR2ADORA1NR1H2EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057739-A | Diazepinone derivatives and their use in the treatment of hepatitis b infections | 诺维拉治疗公司 | 2022-02-18 | — | — | CN | disclosed |