SCHEMBL29386283

SCHEMBL29386283

C[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 12/20 0.58
▸ OPRM1 P35372 5/20 0.58
▸ OPRK1 P41145 1/20 0.58
▸ SLC7A5 Q01650 1/20 0.52
▸ YARS1 P54577 2/20 0.51
▸ MME P08473 1/20 0.50
▸ ACE P12821 1/20 0.50
▸ CPA1 P15085 1/20 0.50
▸ ACE2 Q9BYF1 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31717989 0.92 OPRD1 (0.64) OPRD1OPRM1OPRK1SLC7A5MME
SCHEMBL9852111 0.92 SLC7A5 (0.61) OPRD1OPRM1OPRK1SLC7A5YARS1
SCHEMBL30622026 0.92 SLC7A5 (0.61) OPRD1OPRM1OPRK1SLC7A5YARS1
SCHEMBL9852121 0.92 SLC7A5 (0.61) OPRD1OPRM1OPRK1SLC7A5YARS1
SCHEMBL29431826 0.90 OPRD1 (0.55) OPRD1OPRM1OPRK1SLC7A5YARS1
SCHEMBL31096839 0.90 MME (0.56) OPRD1OPRM1OPRK1SLC7A5MME
SCHEMBL30786035 0.89 OPRD1 (0.69) OPRD1OPRM1OPRK1MMEACE
SCHEMBL30079821 0.89 OPRD1 (0.58) OPRD1OPRM1OPRK1SLC7A5YARS1
SCHEMBL31257080 0.89 OPRD1 (0.63) OPRD1OPRM1OPRK1
SCHEMBL10621141 0.88 OPRD1 (0.61) OPRD1OPRM1OPRK1SLC7A5YARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250026857-A1 MINI BODIES AS VACCINES FOR HIV POMONA RICERCA S.R.L. (IT) 2025-01-23 — — US claimed
EP-4440609-A1 MINI BODIES AS VACCINES FOR HIV Pomona Ricerca S.r.l. (IT) 2024-10-09 — — EP claimed
WO-2023100069-A1 MINI BODIES AS VACCINES FOR HIV POMONA RICERCA S.R.L. (IT) 2023-06-08 — — WO claimed
EP-4678664-A2 ANTI-HUMAN TRANSFERRIN RECEPTOR ANTIBODY PERMEATING BLOOD-BRAIN BARRIER JCR Pharmaceuticals Co., Ltd. (JP) 2026-01-14 — — EP disclosed
EP-3315606-B1 ANTI-HUMAN TRANSFERRIN RECEPTOR ANTIBODY PERMEATING BLOOD-BRAIN BARRIER JAPAN CHEM RES (JP) 2025-11-26 — — EP disclosed
US-20250026857-A1 MINI BODIES AS VACCINES FOR HIV POMONA RICERCA S.R.L. (IT) 2025-01-23 — — US disclosed
US-20240262926-A1 Fusion Protein Containing BDNF JCR PHARMACEUTICALS CO., LTD. (JP) 2024-08-08 — — US disclosed
US-11958905-B2 Fusion proteins containing a BDNF and an anti-human transferrin receptor antibody JCR PHARMACEUTICALS CO., LTD. (JP) 2024-04-16 — — US disclosed
CN-110483637-B Anti-avian influenza virus neuraminidase N2 monoclonal antibody, encoding gene and application thereof 扬州大学 2022-06-10 — — CN disclosed
CN-114409783-A Anti-human transferrin receptor antibodies across the blood brain barrier JCR制药股份有限公司 2022-04-29 — — CN disclosed
EP-3072527-B1 IMMUNOSUPPRESSANT UNIV HOKKAIDO NAT UNIV CORP (JP) 2022-03-09 — — EP disclosed
US-20220064288-A1 Anti-Human Transferrin Receptor Antibody Permeating Blood-Brain Barrier JCR PHARMACEUTICALS CO., LTD. (JP) 2022-03-03 — — US disclosed
US-11248045-B2 Anti-human transferrin receptor antibody permeating blood-brain barrier JCR PHARMACEUTICALS CO., LTD. (JP) 2022-02-15 — — US disclosed
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