Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 11/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | TAS2R8 | Q9NYW2 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2937972 | 0.90 | IGF1R (0.61) | IGF1RRXFP1NAMPTPPARGPPARD | |
| SCHEMBL2939876 | 0.87 | IGF1R (0.60) | IGF1RNAMPT | |
| SCHEMBL2941295 | 0.87 | IGF1R (0.41) | IGF1RTAS2R8PPARGPPARDPPARA | |
| SCHEMBL2933250 | 0.85 | IGF1R (0.57) | IGF1RRXFP1NAMPT | |
| SCHEMBL2939446 | 0.85 | IGF1R (0.61) | IGF1RRXFP1NAMPTPPARGPPARD | |
| SCHEMBL2936682 | 0.84 | IGF1R (0.63) | IGF1RPPARGPPARDPPARA | |
| SCHEMBL2936312 | 0.84 | RXFP1 (0.39) | IGF1RRXFP1NAMPTTAS2R8PPARD | |
| SCHEMBL2941481 | 0.84 | IGF1R (0.62) | IGF1RNAMPTPPARGPPARDPPARA | |
| SCHEMBL2940170 | 0.83 | IGF1R (0.58) | IGF1RRXFP1NAMPT | |
| SCHEMBL2940894 | 0.83 | IGF1R (0.62) | IGF1RNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-B1 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2010-09-22 | — | — | EP | disclosed |