Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 18/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29390070 | 0.86 | RORC (0.59) | RORCPPARGMAP2K3KDM4EMEN1 | |
| SCHEMBL25776035 | 0.84 | RORC (0.62) | RORCPPARGMAP2K3KDM4EMEN1 | |
| SCHEMBL29389092 | 0.84 | RORC (0.65) | RORCPPARGMAP2K3KDM4EMEN1 | |
| SCHEMBL29386615 | 0.83 | RORC (0.61) | RORCPPARGMAP2K3KDM4EMEN1 | |
| SCHEMBL29389352 | 0.82 | RORC (0.60) | RORCPPARGMAP2K3KDM4EMEN1 | |
| SCHEMBL28711290 | 0.81 | RORC (0.59) | RORCPPARGMAP2K3KDM4EMEN1 | |
| SCHEMBL29386833 | 0.81 | RORC (0.64) | RORCPPARGMAP2K3KDM4EMEN1 | |
| SCHEMBL29389794 | 0.81 | RORC (0.56) | RORCPPARGMAP2K3KDM4EMEN1 | |
| SCHEMBL29386498 | 0.78 | RORC (0.56) | RORCPPARGMAP2K3KDM4EMEN1 | |
| SCHEMBL29389090 | 0.78 | RORC (0.56) | RORCPPARGMAP2K3KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109254-A1 | METHOD FOR ONE-STEP DIRECT PREPARATION OF 3-ACYL IMIDAZO[1,5-A]PYRIDINE BY MEANS OF [4+1] DUAL AMINATION REACTIONS OF KETOMETHYL | 安徽科技学院 | 2023-06-22 | — | — | WO | disclosed |
| CN-114057737-B | Method for directly preparing 3-acyl imidazole [1,5-a ] pyridine by one-step secondary amination reaction of [4+1] ketone methyl | 安徽科技学院 | 2022-08-26 | — | — | CN | disclosed |
| CN-114057737-A | Method for directly preparing 3-acyl imidazole [1,5-a ] pyridine by one-step secondary amination reaction of [4+1] ketone methyl | 安徽科技学院 | 2022-02-18 | — | — | CN | disclosed |