Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 9/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | HCK | P08631 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22869347 | 1.00 | QPCT (0.39) | QPCTQPCTLPPARDCYP1A2METAP2 | |
| SCHEMBL22869345 | 0.95 | ALOX5AP (0.38) | QPCTQPCTLPPARDCYP1A2METAP2 | |
| SCHEMBL30477942 | 0.95 | ALOX5AP (0.38) | QPCTQPCTLPPARDCYP1A2METAP2 | |
| SCHEMBL22869354 | 0.94 | QPCT (0.37) | QPCTQPCTLPPARDCYP1A2METAP2 | |
| SCHEMBL29387879 | 0.94 | QPCT (0.37) | QPCTQPCTLPPARDCYP1A2METAP2 | |
| SCHEMBL23054311 | 0.90 | QPCT (0.38) | QPCTQPCTLPPARDCYP1A2METAP2 | |
| SCHEMBL22869350 | 0.88 | QPCT (0.37) | QPCTQPCTLPPARDCYP1A2METAP2 | |
| SCHEMBL30477940 | 0.88 | QPCT (0.37) | QPCTQPCTLPPARDCYP1A2METAP2 | |
| SCHEMBL22869318 | 0.87 | QPCT (0.36) | QPCTQPCTLPPARDCYP1A2METAP2 | |
| SCHEMBL22869282 | 0.86 | QPCT (0.36) | QPCTQPCTLPPARDCYP1A2METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3759096-B1 | CD73 INHIBITORS | LILLY CO ELI (US) | 2022-02-16 | — | — | EP | disclosed |