Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.37 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 14/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 6/20 | 0.34 |
| ▸ | MDM4 | O15151 | 3/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22869350 | 1.00 | QPCT (0.37) | QPCTQPCTLHSD11B1MDM2PPARD | |
| SCHEMBL29384847 | 0.95 | MDM2 (0.36) | QPCTQPCTLHSD11B1MDM2PPARD | |
| SCHEMBL22869370 | 0.95 | MDM2 (0.36) | QPCTQPCTLHSD11B1MDM2PPARD | |
| SCHEMBL29386867 | 0.95 | HSD11B1 (0.36) | QPCTQPCTLHSD11B1MDM2PPARD | |
| SCHEMBL22869358 | 0.95 | HSD11B1 (0.36) | QPCTQPCTLHSD11B1MDM2PPARD | |
| SCHEMBL22869347 | 0.88 | QPCT (0.39) | QPCTQPCTLHSD11B1MDM2PPARD | |
| SCHEMBL29386863 | 0.88 | QPCT (0.39) | QPCTQPCTLHSD11B1MDM2PPARD | |
| SCHEMBL22869344 | 0.88 | HSD11B1 (0.35) | QPCTQPCTLHSD11B1MDM2PPARD | |
| SCHEMBL25840251 | 0.88 | HSD11B1 (0.35) | QPCTQPCTLHSD11B1MDM2PPARD | |
| SCHEMBL26527584 | 0.88 | MDM2 (0.35) | QPCTQPCTLHSD11B1MDM2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005615-A | Pyridazine compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-111819173-B | CD73 inhibitors | 伊莱利利公司 | 2023-06-06 | — | — | CN | disclosed |