Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 10/20 | 1.00 |
| ▸ | AURKB | Q96GD4 | 3/20 | 1.00 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 1.00 |
| ▸ | AURKA | O14965 | 2/20 | 1.00 |
| ▸ | FLT3 | P36888 | 2/20 | 1.00 |
| ▸ | CDC7 | O00311 | 1/20 | 1.00 |
| ▸ | PLK4 | O00444 | 1/20 | 1.00 |
| ▸ | DAPK3 | O43293 | 1/20 | 1.00 |
| ▸ | ROCK2 | O75116 | 1/20 | 1.00 |
| ▸ | PRKD3 | O94806 | 1/20 | 1.00 |
| ▸ | PRKCG | P05129 | 1/20 | 1.00 |
| ▸ | LCK | P06239 | 1/20 | 1.00 |
| ▸ | PIM1 | P11309 | 1/20 | 1.00 |
| ▸ | PRKACA | P17612 | 1/20 | 1.00 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 1.00 |
| ▸ | CDK2 | P24941 | 1/20 | 1.00 |
| ▸ | MARK3 | P27448 | 1/20 | 1.00 |
| ▸ | AKT1 | P31749 | 1/20 | 1.00 |
| ▸ | AKT2 | P31751 | 1/20 | 1.00 |
| ▸ | FLT4 | P35916 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gsk-269962A SCHEMBL29365470 | 1.00 | ROCK1 (1.00) | ROCK1AURKBRPS6KA5AURKAFLT3 | |
| Gsk-269962A SCHEMBL1838346 | 1.00 | ROCK1 (1.00) | ROCK1AURKBRPS6KA5AURKAFLT3 | |
| Gsk-269962A SCHEMBL29715551 | 0.99 | ROCK1 (0.99) | ROCK1AURKBRPS6KA5AURKAFLT3 | |
| SCHEMBL4007749 | 0.95 | ROCK1 (0.90) | ROCK1AURKBRPS6KA5AURKAFLT3 | |
| SCHEMBL4002686 | 0.94 | ROCK1 (0.89) | ROCK1AURKBRPS6KA5AURKAFLT3 | |
| SCHEMBL4003195 | 0.94 | ROCK1 (0.89) | ROCK1AURKBRPS6KA5AURKAFLT3 | |
| SCHEMBL4002266 | 0.94 | ROCK1 (0.88) | ROCK1AURKBRPS6KA5AURKAFLT3 | |
| SCHEMBL4008685 | 0.93 | ROCK1 (0.87) | ROCK1AURKBRPS6KA5AURKAFLT3 | |
| SCHEMBL4004630 | 0.92 | ROCK1 (0.85) | ROCK1AURKBRPS6KA5AURKAFLT3 | |
| SCHEMBL4000210 | 0.91 | ROCK1 (0.84) | ROCK1AURKBRPS6KA5AURKAFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4636079-A1 | METHOD FOR INDUCING DIFFERENTIATION OF STEM CELLS INTO CORNEAL ENDOTHELIAL CELLS AND USE THEREOF | The Asan Foundation (KR) | 2025-10-22 | — | — | EP | claimed |
| WO-2024128696-A1 | METHOD FOR INDUCING DIFFERENTIATION OF STEM CELLS INTO CORNEAL ENDOTHELIAL CELLS AND USE THEREOF | 재단법인 아산사회복지재단 | 2024-06-20 | — | — | WO | claimed |
| EP-4214239-A1 | COMPOSITIONS AND METHODS FOR OVERCOMING DR5-INDUCED IMMUNE EVASION BY SOLID TUMORS | University of Virginia Patent Foundation (US) | 2023-07-26 | — | — | EP | claimed |
| WO-2022081869-A1 | COMPOSITIONS AND METHODS FOR OVERCOMING DR5-INDUCED IMMUNE EVASION BY SOLID TUMORS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2022-04-21 | — | — | WO | claimed |
| EP-4662319-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | Integrate Bioscience LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| EP-4636079-A1 | METHOD FOR INDUCING DIFFERENTIATION OF STEM CELLS INTO CORNEAL ENDOTHELIAL CELLS AND USE THEREOF | The Asan Foundation (KR) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024233940-A1 | CELL REPLACEMENT THERAPY FOR PULMONARY DISEASES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2024-11-14 | — | — | WO | disclosed |
| WO-2024171957-A1 | TRANSPLANTATION OF PITUITARY HORMONE-PRODUCING CELLS | 国立大学法人東海国立大学機構 | 2024-08-22 | — | — | WO | disclosed |
| WO-2024168301-A2 | PERSONALIZED CRISPR PROFILING FOR CANCER | FUNCTION ONCOLOGY, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| CN-112996903-B | Culture medium for directly differentiating pluripotent stem cell-derived mesenchymal stem cells, method for preparing mesenchymal stem cells using same, and mesenchymal stem cells prepared thereby | 车比奥泰有限公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-118318033-A | Cell aggregate comprising pituitary hormone-producing cells and method for producing the same | 住友制药株式会社 | 2024-07-09 | — | — | CN | disclosed |
| WO-2024128696-A1 | METHOD FOR INDUCING DIFFERENTIATION OF STEM CELLS INTO CORNEAL ENDOTHELIAL CELLS AND USE THEREOF | 재단법인 아산사회복지재단 | 2024-06-20 | — | — | WO | disclosed |
| WO-2023054395-A1 | CELL AGGREGATE INCLUDING PITUITARY HORMONE-PRODUCING CELLS AND METHOD FOR PRODUCING SAME | 住友ファーマ株式会社 | 2023-04-06 | — | — | WO | disclosed |
| WO-2023054396-A1 | METHOD FOR PRODUCING CELL MASS INCLUDING PITUITARY TISSUE AND CELL MASS | 住友化学株式会社 | 2023-04-06 | — | — | WO | disclosed |
| WO-2023033137-A1 | KIDNEY ORGANOID AND METHOD FOR PRODUCING SAME | 大塚製薬株式会社 | 2023-03-09 | — | — | WO | disclosed |
| WO-2023277135-A1 | METHOD FOR PRODUCING CELLS CONSTITUTING NASAL EPITHELIUM, AND CELL POPULATION INCLUDING CELLS CONSTITUTING NASAL EPITHELIUM OR PROGENITOR CELLS THEREOF | 住友化学株式会社 | 2023-01-05 | — | — | WO | disclosed |
| WO-2022172960-A1 | MATURATION AGENT | オリヅルセラピューティクス株式会社 | 2022-08-18 | — | — | WO | disclosed |
| EP-4039795-A1 | MEDIUM FOR CULTURING HEPATOCYTES, PRODUCTION METHOD FOR HEPATOCYTES, AND HEPATOCYTES | FUJIFILM Corporation (JP) | 2022-08-10 | — | — | EP | disclosed |
| WO-2022081869-A1 | COMPOSITIONS AND METHODS FOR OVERCOMING DR5-INDUCED IMMUNE EVASION BY SOLID TUMORS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2022-04-21 | — | — | WO | disclosed |
| EP-3945827-A2 | METHODS, COMPOSITIONS, AND KITS FOR PRODUCING SKELETAL MUSCLE STEM CELLS AND TREATING DISORDERS | The Johns Hopkins University (US) | 2022-02-09 | — | — | EP | disclosed |