Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | USP19 | O94966 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15577865 | 1.00 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3CYP2D6USP19 | |
| SCHEMBL7612196 | 0.87 | ROCK2 (0.50) | SLC6A2SLC6A4SLC6A3HCRTR1HCRTR2 | |
| SCHEMBL31086977 | 0.82 | CYP2D6 (0.50) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2A | |
| SCHEMBL15578384 | 0.81 | ROCK1 (0.47) | HCRTR1HCRTR2HTR2CHTR2BUSP30 | |
| SCHEMBL16933690 | 0.81 | ROCK1 (0.47) | HCRTR1HCRTR2HTR2CHTR2BUSP30 | |
| SCHEMBL29384430 | 0.81 | ROCK1 (0.47) | HCRTR1HCRTR2HTR2CHTR2BUSP30 | |
| Hydrochloric Acid SCHEMBL31045930 | 0.81 | CYP2D6 (0.49) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2A | |
| SCHEMBL1205669 | 0.75 | HTR2C (0.52) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2A | |
| SCHEMBL1205545 | 0.75 | HTR2C (0.52) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2A | |
| SCHEMBL15578320 | 0.73 | HCRTR1 (0.47) | HCRTR1HCRTR2USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114533729-A | Glucosylceramide synthase inhibitors | 建新公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-108864076-B | Glucosylceramide synthase inhibitors | 建新公司 | 2022-02-11 | — | — | CN | disclosed |