Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 7/20 | 0.49 |
| ▸ | NPY4R | P50391 | 6/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.47 |
| ▸ | NPY1R | P25929 | 5/20 | 0.47 |
| ▸ | NPY2R | P49146 | 2/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | GLP1R | P43220 | 3/20 | 0.46 |
| ▸ | SCTR | P47872 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CTSH | P09668 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29387939 | 0.94 | PTPN1 (0.48) | BACE1NPY4RNPY5RNPY1RGLP1R | |
| SCHEMBL29519546 | 0.94 | NPY4R (0.45) | BACE1NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL30252503 | 0.93 | NPY4R (0.54) | BACE1NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL29840375 | 0.93 | GLP1R (0.47) | BACE1NPY4RNPY5RNPY1RGLP1R | |
| SCHEMBL29476637 | 0.92 | NPY4R (0.45) | BACE1NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL29476479 | 0.91 | FNTA (0.49) | NPY4RNPY5RNPY1RNPY2RTUBB4A | |
| SCHEMBL29511116 | 0.91 | FNTA (0.47) | NPY4RNPY5RNPY1RNPY2RGLP1R | |
| SCHEMBL29684563 | 0.91 | NPY4R (0.51) | NPY4RNPY5RNPY1RNPY2RGLP1R | |
| SCHEMBL30845345 | 0.90 | NPY4R (0.47) | BACE1NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL30956347 | 0.90 | GLP1R (0.51) | BACE1GLP1RSCTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124612-A1 | MOLECULES WITH ALTERED NEONATE FC RECEPTOR BINDING HAVING ENHANCED THERAPEUTIC AND DIAGNOSTIC PROPERTIES | MEDIMMUNE LLC | 2024-04-18 | — | — | US | disclosed |
| US-11767369-B2 | Molecules with altered neonate Fc receptor binding having enhanced therapeutic and diagnostic properties | MEDIMMUNE, LLC (US) | 2023-09-26 | — | — | US | disclosed |
| CN-106413750-B | Molecules with altered neonatal Fc receptor binding with enhanced therapeutic and diagnostic properties | 免疫医疗有限责任公司 | 2022-04-29 | — | — | CN | disclosed |