Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.36 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.36 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.35 |
| ▸ | HTR1F | P30939 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21062119 | 1.00 | CYP3A4 (0.38) | CYP3A4CYP2D6CYP2C9CYP2C19KCNH2 | |
| SCHEMBL29390977 | 0.84 | DRD4 (0.36) | CYP3A4CYP2D6CYP2C9CYP2C19KCNH2 | |
| SCHEMBL21062175 | 0.84 | DRD4 (0.36) | CYP3A4CYP2D6CYP2C9CYP2C19KCNH2 | |
| SCHEMBL21146069 | 0.84 | ABL1 (0.39) | CYP3A4CYP2D6CYP2C9CYP2C19KCNH2 | |
| SCHEMBL29389917 | 0.84 | ABL1 (0.39) | CYP3A4CYP2D6CYP2C9CYP2C19KCNH2 | |
| SCHEMBL29390420 | 0.82 | CYP3A4 (0.40) | CYP3A4CYP2D6CYP2C9CYP2C19KCNH2 | |
| SCHEMBL21146066 | 0.82 | CYP3A4 (0.40) | CYP3A4CYP2D6CYP2C9CYP2C19KCNH2 | |
| SCHEMBL29390725 | 0.81 | HTR2B (0.42) | HTR2BPOLBMEN1KMT2AHTR1F | |
| SCHEMBL21145868 | 0.81 | HTR2B (0.42) | HTR2BPOLBMEN1KMT2AHTR1F | |
| SCHEMBL21146538 | 0.80 | CYP3A4 (0.41) | CYP3A4CYP2D6CYP2C9CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11247965-B2 | Hepatitis B capsid assembly modulators | VenatoRx Pharmaceuticals, Inc. (US) | 2022-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11247965-B2 | Hepatitis B capsid assembly modulators | HAVCR2, COPB1, HDLBP | CYP3A4 2465/4885CYP2D6 4268/4885CYP2C9 4012/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.