Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 19/20 | 1.00 |
| ▸ | HTR1D | P28221 | 19/20 | 1.00 |
| ▸ | HTR1B | P28222 | 17/20 | 1.00 |
| ▸ | ADRB1 | P08588 | 1/20 | 1.00 |
| ▸ | DRD2 | P14416 | 1/20 | 1.00 |
| ▸ | HTR2A | P28223 | 1/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 1/20 | 1.00 |
| ▸ | HTR7 | P34969 | 1/20 | 1.00 |
| ▸ | DRD3 | P35462 | 1/20 | 1.00 |
| ▸ | HTR2B | P41595 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5364247 | 1.00 | HTR1A (1.00) | HTR1AHTR1DHTR1BADRB1DRD2 | |
| SCHEMBL29462269 | 0.96 | HTR1D (0.93) | HTR1AHTR1DHTR1BADRB1DRD2 | |
| SCHEMBL14564986 | 0.90 | HTR1A (0.82) | HTR1AHTR1DHTR1BADRB1DRD2 | |
| SCHEMBL14565044 | 0.90 | HTR1A (1.00) | HTR1AHTR1DHTR1BADRB1DRD2 | |
| SCHEMBL14564979 | 0.89 | HTR1A (1.00) | HTR1AHTR1DHTR1BADRB1DRD2 | |
| SCHEMBL5213744 | 0.89 | HTR1A (0.85) | HTR1AHTR1DHTR1BADRB1DRD2 | |
| SCHEMBL5364391 | 0.89 | HTR1D (1.00) | HTR1AHTR1DHTR1BADRB1DRD2 | |
| SCHEMBL5216805 | 0.88 | HTR1A (1.00) | HTR1AHTR1DHTR1BADRB1DRD2 | |
| SCHEMBL5369349 | 0.87 | HTR1A (0.76) | HTR1AHTR1DHTR1BADRB1DRD2 | |
| SCHEMBL5251500 | 0.86 | HTR1A (1.00) | HTR1AHTR1DHTR1BADRB1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220146492-A1 | CELL MEMBRANE PERMEABILITY RESTORING THERAPY | SHINE IAN BASIL (US) | 2022-05-12 | — | — | US | claimed |
| EP-3953000-A1 | CELL MEMBRANE PERMEABILITY RESTORING THERAPY | Shine, Ian Basil (US) | 2022-02-16 | — | — | EP | claimed |
| US-12285426-B2 | Combination serotonin specific reuptake inhibitor and serotonin 1A receptor partial agonist for reducing L-DOPA-induced dyskinesia | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2025-04-29 | — | — | US | disclosed |
| US-20220146492-A1 | CELL MEMBRANE PERMEABILITY RESTORING THERAPY | SHINE IAN BASIL (US) | 2022-05-12 | — | — | US | disclosed |
| EP-3953000-A1 | CELL MEMBRANE PERMEABILITY RESTORING THERAPY | Shine, Ian Basil (US) | 2022-02-16 | — | — | EP | disclosed |