SCHEMBL29389345

SCHEMBL29389345

C1CCC(NC2CCCCC2)CC1.CC(C)(C)OC(=O)N[C@@H](CN=[N+]=[N-])C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ HDAC4 P56524 1/20 0.45
▸ HDAC1 Q13547 1/20 0.45
▸ HDAC6 Q9UBN7 1/20 0.45
▸ CTSK P43235 5/20 0.44
▸ CTSS P25774 4/20 0.44
▸ EPHX1 P07099 1/20 0.40
▸ GAA P10253 1/20 0.38
▸ BTK Q06187 1/20 0.36
▸ PPARA Q07869 3/20 0.35
▸ PPARG P37231 2/20 0.35
▸ CACNA1B Q00975 3/20 0.35
▸ ITGB3 P05106 2/20 0.35
▸ ITGA2B P08514 2/20 0.35
▸ IDO1 P14902 1/20 0.35
▸ ACE P12821 1/20 0.34
▸ CTSL P07711 1/20 0.34
▸ CTSB P07858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28019238 0.90 HDAC4 (0.47) HDAC4HDAC1HDAC6CTSKCTSS
SCHEMBL19064542 0.90 HDAC4 (0.47) HDAC4HDAC1HDAC6CTSKCTSS
SCHEMBL29392200 0.87 HDAC4 (0.52) HDAC4HDAC1HDAC6CTSKCTSS
SCHEMBL15156428 0.87 CTSK (0.43) CTSKCTSSPPARAPPARGITGB3
SCHEMBL13483252 0.87 CTSK (0.43) CTSKCTSSPPARAPPARGITGB3
SCHEMBL15157513 0.87 CTSK (0.43) CTSKCTSSPPARAPPARGITGB3
SCHEMBL29398036 0.82 HDAC4 (0.51) HDAC4HDAC1HDAC6CTSKCTSS
SCHEMBL11096628 0.82 HDAC4 (0.51) HDAC4HDAC1HDAC6CTSKCTSS
SCHEMBL29400626 0.82 HDAC4 (0.51) HDAC4HDAC1HDAC6CTSKCTSS
SCHEMBL29401603 0.82 HDAC4 (0.51) HDAC4HDAC1HDAC6CTSKCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260116914-A1 METHODS OF GENERATING NANOARRAYS AND MICROARRAYS NAUTILUS SUBSIDIARY INC (US) 2026-04-30 — — US disclosed
US-20250349136-A1 METHODS AND SYSTEMS FOR COMPUTATIONAL DECODING OF BIOLOGICAL, CHEMICAL, AND PHYSICAL ENTITIES NAUTILUS SUBSIDIARY INC (US) 2025-11-13 — — US disclosed
US-12394223-B2 Methods and systems for computational decoding of biological, chemical, and physical entities NAUTILUS SUBSIDIARY, INC. (US) 2025-08-19 — — US disclosed
US-12306093-B2 Methods and systems for integrated on-chip single-molecule detection NAUTILUS SUBSIDIARY, INC. (US) 2025-05-20 — — US disclosed
US-20240249539-A1 METHODS AND SYSTEMS FOR COMPUTATIONAL DECODING OF BIOLOGICAL, CHEMICAL, AND PHYSICAL ENTITIES NAUTILUS SUBSIDIARY, INC. 2024-07-25 — — US disclosed
US-11935311-B2 Methods and systems for computational decoding of biological, chemical, and physical entities NAUTILUS SUBSIDIARY, INC. (US) 2024-03-19 — — US disclosed
US-20230340014-A1 METHODS OF GENERATING NANOARRAYS AND MICROARRAYS NAUTILUS SUBSIDIARY, INC. 2023-10-26 — — US disclosed
EP-4231174-A2 METHODS AND SYSTEMS FOR COMPUTATIONAL DECODING OF BIOLOGICAL, CHEMICAL, AND PHYSICAL ENTITIES Nautilus Subsidiary, Inc. (US) 2023-08-23 — — EP disclosed
US-20230257416-A1 METHODS OF GENERATING NANOARRAYS AND MICROARRAYS NAUTILUS SUBSIDIARY, INC. 2023-08-17 — — US disclosed
US-20230221243-A1 METHODS AND SYSTEMS FOR INTEGRATED ON-CHIP SINGLE-MOLECULE DETECTION NAUTILUS SUBSIDIARY, INC. 2023-07-13 — — US disclosed
US-20230213438-A1 METHODS AND SYSTEMS FOR INTEGRATED ON-CHIP SINGLE-MOLECULE DETECTION NAUTILUS SUBSIDIARY, INC. 2023-07-06 — — US disclosed
EP-4165549-A1 METHODS AND SYSTEMS FOR COMPUTATIONAL DECODING OF BIOLOGICAL, CHEMICAL, AND PHYSICAL ENTITIES Nautilus Biotechnology, Inc. (US) 2023-04-19 — — EP disclosed
US-11603383-B2 Methods of generating nanoarrays and microarrays NAUTILUS BIOTECHNOLOGY, INC. (US) 2023-03-14 — — US disclosed
US-20220204549-A1 METHODS OF GENERATING NANOARRAYS AND MICROARRAYS NAUTILUS BIOTECHNOLOGY, INC. 2022-06-30 — — US disclosed
EP-3963091-A1 METHODS AND SYSTEMS FOR INTEGRATED ON-CHIP SINGLE-MOLECULE DETECTION Nautilus Biotechnology, Inc. (US) 2022-03-09 — — EP disclosed
US-20220050049-A1 METHODS AND SYSTEMS FOR INTEGRATED ON-CHIP SINGLE-MOLECULE DETECTION NAUTILUS SUBSIDIARY, INC. 2022-02-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260116914-A1 METHODS OF GENERATING NANOARRAYS AND MICROARRAYS SPPL2B, SNAP29, SPPL2A HDAC4 4078/4885HDAC1 4630/4885HDAC6 3818/4885
US-11603383-B2 Methods of generating nanoarrays and microarrays NAPA, SSBP1, NASP HDAC4 3370/4885HDAC1 3396/4885HDAC6 1925/4885
US-20220204549-A1 METHODS OF GENERATING NANOARRAYS AND MICROARRAYS NAPA, SSBP1, NASP HDAC4 3370/4885HDAC1 3396/4885HDAC6 1925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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