Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 5/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL377320 | 0.89 | TP53 (0.56) | TP53LMNACA4OR51E2CA2 | |
| Bicarbonate SCHEMBL5663600 | 0.89 | TP53 (0.56) | TP53LMNACA4OR51E2CA2 | |
| Acetic Acid SCHEMBL377225 | 0.86 | CA1 (0.53) | TP53LMNACA4OR51E2CA2 | |
| L-Lactic Acid SCHEMBL2937453 | 0.78 | TP53 (0.46) | TP53LMNACA4OR51E2CA2 | |
| Acrylic Acid SCHEMBL30986765 | 0.78 | TP53 (0.46) | TP53LMNACA1TSHR | |
| SCHEMBL29465010 | 0.78 | — | — | |
| SCHEMBL29465011 | 0.78 | — | — | |
| Methacrylic Acid SCHEMBL30986764 | 0.76 | TP53 (0.43) | TP53CA4CA1TSHR | |
| Urea SCHEMBL196801 | 0.74 | TP53 (0.47) | TP53LMNAOR51E2CYP3A4 | |
| Sulfurous Acid SCHEMBL11518322 | 0.74 | TP53 (0.56) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3980508-B1 | COMPOSITION FOR ENHANCING INJECTIVITY OF A SUBTERRANEAN FORMATION | TOTALENERGIES ONETECH (FR) | 2025-03-19 | — | — | EP | claimed |
| US-12091608-B2 | Composition for enhancing injectivity of a subterranean formation | TOTALENERGIES ONETECH (FR) | 2024-09-17 | — | — | US | claimed |
| US-20220220359-A1 | Composition for Enhancing Injectivity of a Subterranean Formation | TOTALENERGIES ONETECH (FR) | 2022-07-14 | — | — | US | claimed |
| EP-3980508-A1 | COMPOSITION FOR ENHANCING INJECTIVITY OF A SUBTERRANEAN FORMATION | TotalEnergies SE (FR) | 2022-04-13 | — | — | EP | claimed |
| WO-2020245622-A1 | COMPOSITION FOR ENHANCING INJECTIVITY OF A SUBTERRANEAN FORMATION | TOTAL SE (FR) | 2020-12-10 | — | — | WO | claimed |
| US-10178867-B2 | Treating microbe contamination in water with THP salts and polymeric biopenetrants | SOLVAY SOLUTIONS UK LIMITED (GB) | 2019-01-15 | — | — | US | claimed |
| US-20180064112-A1 | SYNERGISTIC COMPOSITION | SOLVAY SOLUTIONS UK LTD (GB) | 2018-03-08 | — | — | US | claimed |
| EP-2707376-B1 | METHODS FOR CONTROLLING DEPOLYMERIZATION OF POLYMER COMPOSITIONS | RHODIA OPERATIONS (FR) | 2016-11-30 | — | — | EP | claimed |
| US-9091020-B2 | Flame resistant fabrics and process for making | MILLIKEN & COMPANY (US) | 2015-07-28 | — | — | US | claimed |
| EP-2396170-B1 | METHODS FOR CONTROLLING DEPOLYMERIZATION OF POLYMER COMPOSITIONS | RHODIA OPERATIONS (FR) | 2015-03-25 | — | — | EP | claimed |
| US-8828914-B2 | Methods for controlling depolymerization of polymer compositions | RHODIA OPERATIONS (FR) | 2014-09-09 | — | — | US | claimed |
| EP-2707376-A2 | METHODS FOR CONTROLLING DEPOLYMERIZATION OF POLYMER COMPOSITIONS | Rhodia Operations S.A. (FR) | 2014-03-19 | — | — | EP | claimed |
| WO-2012154785-A2 | METHODS FOR CONTROLLING DEPOLYMERIZATION OF POLYMER COMPOSITIONS | RHODIA OPERATIONS (FR) | 2012-11-15 | — | — | WO | claimed |
| US-20120289436-A1 | METHODS FOR CONTROLLING DEPOLYMERIZATION OF POLYMER COMPOSITIONS | RHODIA OPERATIONS (FR) | 2012-11-15 | — | — | US | claimed |
| WO-2010093473-A1 | METHODS FOR CONTROLLING DEPOLYMERIZATION OF POLYMER COMPOSITIONS | RHODIA OPERATIONS (FR) | 2010-08-19 | — | — | WO | claimed |
| US-20100204068-A1 | Methods for controlling depolymerization of polymer compositions | RHODIA OPERATIONS (FR) | 2010-08-12 | — | — | US | claimed |
| US-7214292-B2 | Addition of THP or THP+ salt to pulping liquors to destroy catalase and/or catalase producing bacteria | RHODIA CONSUMER SPECIALTIES LIMITED (GB) | 2007-05-08 | — | — | US | claimed |
| EP-3980508-B1 | COMPOSITION FOR ENHANCING INJECTIVITY OF A SUBTERRANEAN FORMATION | TOTALENERGIES ONETECH (FR) | 2025-03-19 | — | — | EP | disclosed |
| US-5578694-A | MELT POLYCONDENSATION OF AROMATIC DIOL AND DIARYL CARBONATE; ESTER INTERCHANGE USING PHOSPHONIUM CATALYST | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0703262-A2 | Process for producing aromatic polycarbonate | Mitsubishi Chemical Corporation (JP) | 1996-03-27 | — | — | EP | disclosed |