Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 5/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CDC25B | P30305 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | ELANE | P08246 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | S100A4 | P26447 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.52 |
| ▸ | ATG4B | Q9Y4P1 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181722 | 1.00 | PTPRC (0.55) | PTPRCPTPN1MEN1KMT2ACDC25B | |
| SCHEMBL3894758 | 0.98 | MEN1 (0.57) | PTPRCPTPN1MEN1KMT2ACDC25B | |
| SCHEMBL13487409 | 0.95 | PTPRC (0.60) | PTPRCPTPN1MEN1KMT2ACDC25B | |
| SCHEMBL30886642 | 0.95 | PTPRC (0.60) | PTPRCPTPN1MEN1KMT2ACDC25B | |
| SCHEMBL563010 | 0.95 | MEN1 (0.55) | PTPRCPTPN1MEN1KMT2ACDC25B | |
| SCHEMBL13487417 | 0.91 | PTPRC (0.59) | PTPRCPTPN1MEN1KMT2ACDC25B | |
| SCHEMBL9811010 | 0.91 | CA1 (0.48) | PTPRCPTPN1NPC1RAB9AALDH1A1 | |
| SCHEMBL30479662 | 0.91 | CA1 (0.52) | PTPRCPTPN1ALDH1A1CYP3A4S100A4 | |
| SCHEMBL7432075 | 0.91 | CA1 (0.52) | PTPRCPTPN1ALDH1A1CYP3A4S100A4 | |
| SCHEMBL9328908 | 0.91 | CA1 (0.52) | PTPRCPTPN1MEN1KMT2ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4438693-A2 | HETEROCYCLIC SPIRO COMPOUNDS | Merck Patent GmbH (DE) | 2024-10-02 | — | — | EP | disclosed |
| EP-3708634-B1 | HETEROCYCLIC SPIRO COMPOUNDS | MERCK PATENT GMBH (DE) | 2024-08-14 | — | — | EP | disclosed |
| EP-3946712-A1 | A SOLVENT DRYING COMPOSITION AND PROCESSES THERFOR | Aquafortus Technologies Limited (NZ) | 2022-02-09 | — | — | EP | disclosed |