SCHEMBL181722

SCHEMBL181722

O=C1c2ccccc2-c2ccc(F)cc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 5/20 0.55
PTPN1 P18031 2/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
CDC25B P30305 1/20 0.55
NPC1 O15118 6/20 0.54
RAB9A P51151 6/20 0.54
ALDH1A1 P00352 6/20 0.54
SMN1; SMN2 Q16637 5/20 0.54
MAPK1 P28482 4/20 0.54
TP53 P04637 2/20 0.54
CYP3A4 P08684 2/20 0.54
ELANE P08246 1/20 0.54
TSHR P16473 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
S100A4 P26447 3/20 0.52
LMNA P02545 3/20 0.52
PLA2G1B P04054 3/20 0.52
ATG4B Q9Y4P1 3/20 0.52
MAPT P10636 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29390818 1.00 PTPRC (0.55) PTPRCPTPN1MEN1KMT2ACDC25B
SCHEMBL3894758 0.98 MEN1 (0.57) PTPRCPTPN1MEN1KMT2ACDC25B
SCHEMBL13487409 0.95 PTPRC (0.60) PTPRCPTPN1MEN1KMT2ACDC25B
SCHEMBL30886642 0.95 PTPRC (0.60) PTPRCPTPN1MEN1KMT2ACDC25B
SCHEMBL563010 0.95 MEN1 (0.55) PTPRCPTPN1MEN1KMT2ACDC25B
SCHEMBL13487417 0.91 PTPRC (0.59) PTPRCPTPN1MEN1KMT2ACDC25B
SCHEMBL9811010 0.91 CA1 (0.48) PTPRCPTPN1NPC1RAB9AALDH1A1
SCHEMBL30479662 0.91 CA1 (0.52) PTPRCPTPN1ALDH1A1CYP3A4S100A4
SCHEMBL7432075 0.91 CA1 (0.52) PTPRCPTPN1ALDH1A1CYP3A4S100A4
SCHEMBL9328908 0.91 CA1 (0.52) PTPRCPTPN1MEN1KMT2ACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 434 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118834119-A Method for synthesizing bisphenol compound by catalysis of supported ionic liquid 郑州中科新兴产业技术研究院 2024-10-25 CN claimed
CN-111885914-A Compositions and methods for producing expanded hematopoietic stem cells using fluorene derivatives 投资健康有限责任公司 2020-11-03 CN claimed
EP-3700334-A1 COMPOSITIONS AND METHODS OF MAKING EXPANDED HEMATOPOIETIC STEM CELLS USING DERIVATIVES OF FLUORENE Transfusion Health, LLC (US) 2020-09-02 EP claimed
US-20200255371-A1 COMPOSITIONS AND METHODS OF MAKING EXPANDED HEMATOPOIETIC STEM CELLS USING DERIVATIVES OF FLUORENE IMMUNEBRIDGE LLC 2020-08-13 US claimed
US-6368778-B1 FLUORENONE, FLUORENE, COUMARIN, NAPHTHALIC ACID IMIDE, PYRAZOLINE, OR ANTHRACENE IMAGE STABILIZER COMPOUNDS IN THE SILVER LAYER REDUCE IMAGE BROWNING; STABLE TO LIGHT AND HEAT OVER TIME PARTICULARLY UNDER LIGHT-BOX CONDITIONS EASTMAN KODAK COMPANY 2002-04-09 US claimed
US-5914431-A Cocatalysts for the synthesis of bisphenols BAYER AG (DE) 1999-06-22 US claimed
CN-122056781-A Two-part dental sealant, method of administration with a syringe device, and kit 舒万诺知识产权公司 2026-05-19 CN disclosed
EP-3700334-B1 COMPOSITIONS AND METHODS OF MAKING EXPANDED HEMATOPOIETIC STEM CELLS USING DERIVATIVES OF FLUORENE IMMUNEBRIDGE INC (US) 2026-04-08 EP disclosed
EP-4514304-B1 DENTAL COMPOSITION CONTAINING A RESORCINOL OR CATECHOL MOIETY CONTAINING COMPONENT AND USE THEREOF SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-25 EP disclosed
US-12577340-B2 Storage stable two-component dual cure dental composition SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-17 US disclosed
EP-4629958-A1 SURFACE-TREATED FILLER, DENTAL COMPOSITION CONTAINING SUCH A FILLER, PROCESS OF PRODUCTION AND USE THEREOF Solventum Intellectual Properties Company (US) 2025-10-15 EP disclosed
EP-3880156-B1 STORAGE STABLE TWO-COMPONENT DUAL CURE DENTAL COMPOSITION SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-08-20 EP disclosed
US-12311037-B2 Dental composition containing a resorcinol or catechol moiety containing component and use thereof SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-05-27 US disclosed
US-4735632-A RAPID AND DEEP CURE OF BINDER OF MONOMER, ARYLIDONIUM SALT, SENSITIZER, AND ELECTRON DONOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-04-05 US disclosed
US-4540700-A Treatment of diabetic complications with certain spiro-imidazolidine-diones ALCON LABORATORIES, INC. (US) 1985-09-10 US disclosed
US-4537892-A ANTIDIABETIC AGENTS ALCON LABORATORIES, INC. (US) 1985-08-27 US disclosed
US-4438272-A COMPLICATIONS OF DIABETES ALCON LABORATORIES, INC. (US) 1984-03-20 US disclosed
US-4436745-A TETRACYCLIC SPIROHYDANTOINS ALCON LABORATORIES, INC. (US) 1984-03-13 US disclosed
WO-1983003543-A1 METHOD OF INHIBITING ALDOSE REDUCTASE ACTIVITY, COMPOSITIONS THEREFOR AND PROCESS FOR PREPARING SPIRO-FLUOROFLUOREN AND SPIRO-DIFLUOROFLUOREN COMPOUNDS ALCON LAB INC (US) 1983-10-27 WO disclosed
EP-0092385-A2 Hydantoin derivatives for use in inhibiting aldose reductase activity, compositions therefor and process for preparing spiro-fluoren compounds ALCON LABORATORIES, INC. (US) 1983-10-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12311037-B2 Dental composition containing a resorcinol or catechol moiety containing component and use thereof RDX, RECQL, RHOC PTPRC 4232/4885PTPN1 4363/4885MEN1 3966/4885
US-20200255371-A1 COMPOSITIONS AND METHODS OF MAKING EXPANDED HEMATOPOIETIC STEM CELLS USING DERIVATIVES OF FLUORENE FLI1, MCL1, HCLS1 PTPRC 1353/4885PTPN1 2109/4885MEN1 1060/4885
US-12577340-B2 Storage stable two-component dual cure dental composition GPX4, SSRP1, H1-0 PTPRC 2425/4885PTPN1 3305/4885MEN1 4117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.