Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 19/20 | 1.00 |
| ▸ | ABL1 | P00519 | 9/20 | 1.00 |
| ▸ | PIK3CD | O00329 | 4/20 | 1.00 |
| ▸ | PRKDC | P78527 | 4/20 | 1.00 |
| ▸ | PIK3CA | P42336 | 3/20 | 1.00 |
| ▸ | PIK3CB | P42338 | 3/20 | 1.00 |
| ▸ | PIK3CG | P48736 | 3/20 | 1.00 |
| ▸ | EGFR | P00533 | 2/20 | 0.72 |
| ▸ | KDR | P35968 | 2/20 | 0.72 |
| ▸ | MTOR | P42345 | 2/20 | 0.72 |
| ▸ | HCK | P08631 | 1/20 | 0.72 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | PLK4 | O00444 | 1/20 | 0.67 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.67 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.67 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.67 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1964558 | 1.00 | SRC (1.00) | SRCABL1PIK3CDPRKDCPIK3CA | |
| SCHEMBL29390060 | 1.00 | SRC (1.00) | SRCABL1PIK3CDPRKDCPIK3CA | |
| SCHEMBL17637855 | 0.89 | SRC (0.80) | SRCABL1PIK3CDPRKDCPIK3CA | |
| SCHEMBL14617291 | 0.87 | SRC (1.00) | SRCABL1PIK3CDPRKDCPIK3CA | |
| SCHEMBL14617304 | 0.86 | SRC (1.00) | SRCABL1PIK3CDPRKDCPIK3CA | |
| SCHEMBL14617301 | 0.86 | SRC (0.89) | SRCABL1PIK3CDPRKDCPIK3CA | |
| SCHEMBL14617294 | 0.85 | SRC (1.00) | SRCABL1PIK3CDPRKDCPIK3CA | |
| SCHEMBL3610160 | 0.85 | SRC (0.95) | SRCABL1PIK3CDPRKDCPIK3CA | |
| SCHEMBL409031 | 0.84 | SRC (1.00) | SRCABL1PIK3CDPRKDCPIK3CA | |
| SCHEMBL13845116 | 0.84 | SRC (0.72) | SRCABL1PIK3CDPRKDCPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11247972-B2 | Compositions and methods for treating toxoplasmosis, cryptosporidiosis, and other apicomplexan protozoan related diseases | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2022-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11247972-B2 | Compositions and methods for treating toxoplasmosis, cryptosporidiosis, and other apicomplexan protozoan related diseases | PNCK, TXK, CILK1 | SRC 132/4885ABL1 1181/4885PIK3CD 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.