SCHEMBL29391100

SCHEMBL29391100

O=C(O)c1cc(NCc2ccc(F)cc2)ccc1O

nearest known ligand 0.92

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 4/20 0.92
STING1 Q86WV6 1/20 0.92
KDM4C Q9H3R0 4/20 0.74
NOX4 Q9NPH5 2/20 0.59
RGS12 O14924 1/20 0.59
ALDH1A1 P00352 1/20 0.59
EGFR P00533 1/20 0.59
LCK P06239 1/20 0.59
MAPT P10636 1/20 0.59
CAMKK2 Q96RR4 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
GAA P10253 1/20 0.59
P4HTM Q9NXG6 1/20 0.56
SYK P43405 1/20 0.54
KLKB1 P03952 1/20 0.50
CTSB P07858 1/20 0.50
MMP9 P14780 1/20 0.50
DNMT1 P26358 1/20 0.50
DNMT3B Q9UBC3 1/20 0.50
DNMT3L Q9UJW3 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL609562 1.00 PPARA (0.92) PPARASTING1KDM4CNOX4RGS12
SCHEMBL31227828 0.96 PPARA (1.00) PPARASTING1KDM4CNOX4RGS12
SCHEMBL3300413 0.88 PPARA (0.73) PPARASTING1KDM4CNOX4RGS12
SCHEMBL29532272 0.86 KDM4C (0.76) PPARASTING1KDM4CNOX4RGS12
SCHEMBL611490 0.86 KDM4C (0.76) PPARASTING1KDM4CNOX4RGS12
SCHEMBL607997 0.85 KDM4C (0.74) PPARASTING1KDM4CNOX4RGS12
SCHEMBL29388557 0.85 KDM4C (0.74) PPARASTING1KDM4CNOX4RGS12
SCHEMBL607642 0.85 PPARA (0.68) PPARASTING1KDM4CNOX4RGS12
SCHEMBL607106 0.85 KDM4C (0.69) PPARASTING1KDM4CNOX4RGS12
SCHEMBL29390491 0.85 PPARA (0.68) PPARASTING1KDM4CNOX4RGS12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4456890-A2 COMPOSITIONS AND METHODS FOR TREATING PULMONARY DISORDERS GNT Pharma Co., Ltd (KR) 2024-11-06 EP claimed
WO-2023156808-A2 COMPOSITIONS AND METHODS FOR TREATING PULMONARY DISORDERS GNT PHARMA CO., LTD. (KR) 2023-08-24 WO claimed
CN-114096227-A Cosmetic compositions comprising 5-benzylaminosalicylic acid derivatives and methods of topical use thereof 吉恩特药业株式会社 2022-02-25 CN claimed
EP-4456890-A2 COMPOSITIONS AND METHODS FOR TREATING PULMONARY DISORDERS GNT Pharma Co., Ltd (KR) 2024-11-06 EP disclosed
CN-114096227-B Cosmetic compositions comprising 5-benzylaminosalicylic acid derivatives and methods of topical use thereof 吉恩特药业株式会社 2023-11-07 CN disclosed
WO-2023156808-A2 COMPOSITIONS AND METHODS FOR TREATING PULMONARY DISORDERS GNT PHARMA CO., LTD. (KR) 2023-08-24 WO disclosed
CN-114096227-A Cosmetic compositions comprising 5-benzylaminosalicylic acid derivatives and methods of topical use thereof 吉恩特药业株式会社 2022-02-25 CN disclosed