SCHEMBL611490

SCHEMBL611490

O=C(O)c1cc(NCc2ccccc2)ccc1O

nearest known ligand 0.76

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 4/20 0.76
NOX4 Q9NPH5 3/20 0.73
PPARA Q07869 1/20 0.70
STING1 Q86WV6 1/20 0.70
EGFR P00533 6/20 0.64
ALDH1A1 P00352 3/20 0.64
MAPT P10636 2/20 0.64
RGS12 O14924 1/20 0.64
LCK P06239 1/20 0.64
CAMKK2 Q96RR4 1/20 0.64
TDP1 Q9NUW8 1/20 0.64
SYK P43405 2/20 0.60
HNF4A P41235 1/20 0.57
KDM4E B2RXH2 2/20 0.56
GAA P10253 1/20 0.56
HPGD P15428 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29532272 1.00 KDM4C (0.76) KDM4CNOX4PPARASTING1EGFR
SCHEMBL31227771 0.91 PPARA (0.80) KDM4CNOX4PPARASTING1EGFR
SCHEMBL7079654 0.87 KDM4C (0.58) KDM4CNOX4PPARASTING1ALDH1A1
SCHEMBL1403591 0.87 KDM4E (0.59) KDM4CNOX4PPARASTING1ALDH1A1
SCHEMBL10811982 0.86 KDM4C (0.70) KDM4CNOX4PPARASTING1EGFR
SCHEMBL29391100 0.86 PPARA (0.92) KDM4CNOX4PPARASTING1EGFR
SCHEMBL609562 0.86 PPARA (0.92) KDM4CNOX4PPARASTING1EGFR
SCHEMBL29388557 0.86 KDM4C (0.74) KDM4CNOX4PPARASTING1EGFR
SCHEMBL607997 0.86 KDM4C (0.74) KDM4CNOX4PPARASTING1EGFR
SCHEMBL6720218 0.85 HNF4A (0.59) KDM4CNOX4PPARASTING1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3902536-B1 COMPOSITIONS COMPRISING 5-BENZYLAMINOSALICYLIC ACID COMPOUNDS FOR USE IN TREATING NEURODEGENERATIVE DISORDERS IN A COMPANION ANIMAL GNT PHARMA CO LTD (KR) 2025-09-03 EP claimed
WO-2023156808-A2 COMPOSITIONS AND METHODS FOR TREATING PULMONARY DISORDERS GNT PHARMA CO., LTD. (KR) 2023-08-24 WO claimed
US-20230233503-A1 COMPOSITIONS AND METHODS FOR TREATING PULMONARY DISORDERS GNT PHARMA CO., LTD. (KR) 2023-07-27 US claimed
US-20220249343-A1 COSMETIC COMPOSITION INCLUDING 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE, AND TOPICAL USE THEREOF GNT PHARMA CO., LTD. (KR) 2022-08-11 US claimed
US-20220241231-A1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS GNT PHARMA CO., LTD. (KR) 2022-08-04 US claimed
EP-3998058-A1 COSMETIC COMPOSITION COMPRISING 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE AND LOCAL ADMINISTRATION METHOD THEREOF GNT Pharma Co., Ltd (KR) 2022-05-18 EP claimed
CN-114096227-A Cosmetic compositions comprising 5-benzylaminosalicylic acid derivatives and methods of topical use thereof 吉恩特药业株式会社 2022-02-25 CN claimed
CN-113710242-A Compositions and methods for treating neurodegenerative disorders 吉恩特药业株式会社 2021-11-26 CN claimed
EP-3902536-A1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS GNT Pharma Co., Ltd (KR) 2021-11-03 EP claimed
WO-2021006637-A1 COSMETIC COMPOSITION COMPRISING 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE AND LOCAL ADMINISTRATION METHOD THEREOF 주식회사 지엔티파마 2021-01-14 WO claimed
US-20120040939-A1 MEDICINAL USE OF 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE OR ITS SALT NEUROTECH PHARMACEUTICALS CO., LTD. (KR) 2012-02-16 US claimed
CN-102316863-A The medical usage of 5-benzylamino salicyclic acid derivatives or its salt NEUROTECH PHARMACEUTICALS CO L 2012-01-11 CN claimed
US-20070298129-A1 Compounds and compositions for treating neuronal death or neurological dysfunction NEUROTECH PHARMACEUTICALS CO., LTD. (KR) 2007-12-27 US claimed
US-20070049565-A1 Combination of cell necrosis inhibitor and lithium for treating neuronal death or neurological dysfunction NEUROTECH PHARMACEUTICALS CO., LTD. (KR) 2007-03-01 US claimed
CN-1738627-A Method for inhibiting necrosis induced by neurotrophic factor NEUROTECH PHARMACEUTICALS CO L (KR) 2006-02-22 CN claimed
US-6964982-B2 Compounds, compositions and methods for preventing neurodegeneration in acute and chronic injuries in the central nervous system NEUROTECH CO., LTD. (KR) 2005-11-15 US claimed
EP-1274675-B1 COMPOUNDS, COMPOSITIONS AND METHODS FOR PREVENTING NEURODEGENERATION IN ACUTE AND CHRONIC INJURIES IN THE CENTRAL NERVOUS SYSTEM NEUROTECH CO LTD (KR) 2004-09-01 EP claimed
US-20030045575-A1 Compounds, compositions and methods for preventing neurodegeneration in acute and chronic injuries in the central nervous system NEUROTECH CO., LTD. 2003-03-06 US claimed
EP-1274675-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR PREVENTING NEURODEGENERATION IN ACUTE AND CHRONIC INJURIES IN THE CENTRAL NERVOUS SYSTEM Neurotech Co., Ltd. (KR) 2003-01-15 EP claimed
WO-2001079153-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR PREVENTING NEURODEGENERATION IN ACUTE AND CHRONIC INJURIES IN THE CENTRAL NERVOUS SYSTEM NEUROTECH CO., LTD. (KR) 2001-10-25 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230233503-A1 COMPOSITIONS AND METHODS FOR TREATING PULMONARY DISORDERS HAO2, ACOX1, HAO1 KDM4C 3145/4885NOX4 195/4885PPARA 813/4885
US-20220241231-A1 COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS PRNP, PSEN1, GRIK5 KDM4C 2280/4885NOX4 4612/4885PPARA 3388/4885
US-20070298129-A1 Compounds and compositions for treating neuronal death or neurological dysfunction BCL2, BAX, SMN1; SMN2 KDM4C 3544/4885NOX4 2363/4885PPARA 1265/4885
US-20120040939-A1 MEDICINAL USE OF 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE OR ITS SALT HTR5A, HTR6, MC5R KDM4C 2416/4885NOX4 1222/4885PPARA 1630/4885
US-20070049565-A1 Combination of cell necrosis inhibitor and lithium for treating neuronal death or neurological dysfunction BAD, MAP1LC3B, XIAP KDM4C 4402/4885NOX4 763/4885PPARA 4072/4885
US-20220249343-A1 COSMETIC COMPOSITION INCLUDING 5-BENZYLAMINOSALICYLIC ACID DERIVATIVE, AND TOPICAL USE THEREOF ALOX5, ALOX15, IL5 KDM4C 1095/4885NOX4 1921/4885PPARA 908/4885
US-20030045575-A1 Compounds, compositions and methods for preventing neurodegeneration in acute and chronic injuries in the central nervous system GRIK5, GRIN2A, GRIN2C KDM4C 1099/4885NOX4 772/4885PPARA 1754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.