⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL190657 | 1.00 | — | — | |
| SCHEMBL29398110 | 1.00 | — | — | |
| SCHEMBL338633 | 0.79 | — | — | |
| SCHEMBL10620493 | 0.79 | — | — | |
| SCHEMBL1367110 | 0.75 | — | — | |
| SCHEMBL1143136 | 0.75 | — | — | |
| SCHEMBL3576251 | 0.75 | — | — | |
| SCHEMBL12992242 | 0.75 | — | — | |
| SCHEMBL1186659 | 0.75 | — | — | |
| SCHEMBL31321833 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954659-A | Preparation method of arbeli intermediate | 昊宏(齐河)医药科技有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-119431398-A | Anti-tumor application of R406 and derivatives thereof in cooperation with TRAIL | 中国科学院上海有机化学研究所 | 2025-02-14 | — | — | CN | disclosed |
| CN-115974845-B | Preparation method of Ornitinib intermediate | 奥锐特药业股份有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-117720518-B | Benzimidazole compound, preparation method thereof, pharmaceutical composition and application | 江苏海洋大学 | 2024-08-13 | — | — | CN | disclosed |
| CN-114885607-B | Quinolinylphosphine oxide compounds, compositions and uses thereof | 贝达药业股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-113544191-B | Laminate for high-frequency circuit, method for producing same, flexible printed board, B-stage sheet, and laminate roll | JSR株式会社 | 2024-03-29 | — | — | CN | disclosed |
| CN-117720518-A | Benzimidazole compound, preparation method thereof, pharmaceutical composition and application | 江苏海洋大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-113861407-B | Polymer, composition, and molded article | JSR株式会社 | 2024-02-20 | — | — | CN | disclosed |
| CN-114105887-B | Aminopyrimidine derivative and preparation method and application thereof | 沈阳药科大学 | 2023-12-01 | — | — | CN | disclosed |
| CN-116670127-A | EGFR inhibitors and compositions and uses thereof | 贝达药业股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-110831940-B | New substituted azaindoline derivatives as NIK inhibitors | 詹森药业有限公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-115974845-A | Preparation method of oxitinib intermediate | 奥锐特药业股份有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-114885607-A | Quinolylphosphine oxygen compounds, compositions and uses thereof | 贝达药业股份有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-114853740-A | Preparation method and application of alkyne pyrimidine compound as FGFR inhibitor | 药雅科技(上海)有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-109689645-B | Cyanoindoline derivatives as NIK inhibitors | 杨森制药有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-114105887-A | Aminopyrimidine derivative and preparation method and application thereof | 沈阳药科大学 | 2022-03-01 | — | — | CN | disclosed |