Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 7/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25289208 | 1.00 | DGAT1 (0.45) | DGAT1ALOX5APFEN1CCNCCDK8 | |
| SCHEMBL25249478 | 0.89 | DGAT1 (0.42) | DGAT1ALOX5APFEN1CCNCCDK8 | |
| SCHEMBL30531855 | 0.84 | DGAT1 (0.37) | DGAT1ALOX5APFEN1 | |
| SCHEMBL30531851 | 0.82 | DGAT1 (0.40) | DGAT1 | |
| SCHEMBL30531846 | 0.81 | DGAT1 (0.37) | DGAT1ALOX5APFEN1 | |
| SCHEMBL25284186 | 0.81 | DGAT1 (0.41) | DGAT1ALOX5APFEN1CCNCCDK8 | |
| SCHEMBL25239322 | 0.81 | DGAT1 (0.41) | DGAT1ALOX5APFEN1CCNCCDK8 | |
| SCHEMBL29394926 | 0.81 | DGAT1 (0.41) | DGAT1ALOX5APFEN1CCNCCDK8 | |
| SCHEMBL25760802 | 0.81 | DGAT1 (0.48) | DGAT1ALOX5APFEN1 | |
| SCHEMBL25237150 | 0.81 | DGAT1 (0.36) | DGAT1ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119343343-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2025-01-21 | — | — | CN | disclosed |
| EP-4476216-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2024-12-18 | — | — | EP | disclosed |
| EP-4476213-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2024-12-18 | — | — | EP | disclosed |
| CN-119072474-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2024-12-03 | — | — | CN | disclosed |
| WO-2023151574-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO INC. (US) | 2023-08-17 | — | — | WO | disclosed |
| CN-116323599-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2023-06-23 | — | — | CN | disclosed |
| EP-4192831-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022028572-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2022-02-10 | — | — | WO | disclosed |