SCHEMBL2939573

SCHEMBL2939573

CC1(C)C(=O)N(c2ccc(C(F)(F)F)cc2S)C(=O)N1Cc1ccnc(NC(=O)CCN2CCCCC2)c1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 18/20 0.49
TERT O14746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2938067 0.99 IGF1R (0.50) IGF1RTERT
SCHEMBL2933343 0.95 IGF1R (0.50) IGF1R
SCHEMBL2939986 0.93 IGF1R (0.49) IGF1RTERT
SCHEMBL2941088 0.93 IGF1R (0.48) IGF1R
SCHEMBL2995898 0.92 IGF1R (0.51) IGF1R
SCHEMBL2940303 0.91 IGF1R (0.46) IGF1RTERT
SCHEMBL2938645 0.91 IGF1R (0.47) IGF1R
SCHEMBL2941363 0.89 IGF1R (0.48) IGF1R
SCHEMBL2936413 0.89 IGF1R (0.45) IGF1R
SCHEMBL2942267 0.89 IGF1R (0.47) IGF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1599464-B1 NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS AVENTIS PHARMA SA (FR) 2010-09-22 EP disclosed