Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 16/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2941363 | 0.92 | IGF1R (0.48) | IGF1R | |
| SCHEMBL2933343 | 0.89 | IGF1R (0.50) | IGF1RLMNA | |
| SCHEMBL2938067 | 0.89 | IGF1R (0.50) | IGF1R | |
| SCHEMBL2941088 | 0.89 | IGF1R (0.48) | IGF1RSMN1; SMN2 | |
| SCHEMBL2939573 | 0.89 | IGF1R (0.49) | IGF1R | |
| SCHEMBL2940303 | 0.89 | IGF1R (0.46) | IGF1RGAASMN1; SMN2 | |
| SCHEMBL2939986 | 0.88 | IGF1R (0.49) | IGF1R | |
| SCHEMBL2943419 | 0.84 | IGF1R (0.55) | IGF1R | |
| SCHEMBL2935797 | 0.84 | IGF1R (0.69) | IGF1R | |
| SCHEMBL2936413 | 0.84 | IGF1R (0.45) | IGF1RGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599464-B1 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA SA (FR) | 2010-09-22 | — | — | EP | disclosed |
| EP-1599464-A2 | NOVEL CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004070050-A2 | CYCLIC UREA DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL USE OF SAME AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-08-19 | — | — | WO | disclosed |