SCHEMBL293958

SCHEMBL293958

NC(=O)c1ccc(F)cc1F

nearest known ligand 0.68

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.68
CES1 P23141 3/20 0.68
DGAT1 O75907 1/20 0.64
PARP1 P09874 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
MAPK8 P45983 1/20 0.45
KEAP1 Q14145 1/20 0.45
PARP10 Q53GL7 3/20 0.45
PARP15 Q460N3 1/20 0.45
ALDH1A1 P00352 1/20 0.44
PARP14 Q460N5 1/20 0.44
HTT P42858 1/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29758181 1.00 CES2 (0.68) CES2CES1DGAT1PARP1L3MBTL1
Hydrochloric Acid SCHEMBL30628427 0.98 CES2 (0.65) CES2CES1DGAT1PARP1L3MBTL1
Hydrochloric Acid SCHEMBL3851067 0.98 CES2 (0.65) CES2CES1DGAT1PARP1L3MBTL1
Hydrochloric Acid SCHEMBL30458018 0.98 CES2 (0.65) CES2CES1DGAT1PARP1L3MBTL1
Trifluoroacetic Acid SCHEMBL4243581 0.89 CES2 (0.55) CES2CES1DGAT1PARP1L3MBTL1
SCHEMBL30458221 0.89 CES2 (0.55) CES2CES1DGAT1L3MBTL1MAPK8
SCHEMBL29463969 0.84 CES2 (0.52) CES2CES1DGAT1PARP1MAPK8
SCHEMBL30954392 0.82 CES2 (0.68) CES2CES1DGAT1L3MBTL1ALDH1A1
SCHEMBL29537903 0.82 CES2 (0.68) CES2CES1DGAT1PARP1MAPK8
SCHEMBL366058 0.82 CES2 (0.68) CES2CES1DGAT1PARP1MAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 646 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3045206-B2 POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY VIIV HEALTHCARE CO (US) 2023-02-15 EP claimed
CN-114914362-A Preparation method of efficient and stable titanium ore solar cell 西安电子科技大学 2022-08-16 CN claimed
EP-3601296-B1 2-OXO-THIAZOLE DERIVATIVES AS A2A INHIBITORS AND COMPOUNDS FOR USE IN THE TREATMENT OF CANCERS iTeos Belgium SA (BE) 2022-05-25 EP claimed
CN-113195084-A Benzoxazoles and related compounds useful as modulators of molecular chaperone-mediated autophagy 阿尔伯爱因斯坦医学院 2021-07-30 CN claimed
CN-108947868-B Preparation process of 2, 4-difluorobenzonitrile 山东师范大学 2021-02-23 CN claimed
CN-110642741-A Functionalized benzamide derivatives as antiviral agents against HBV infection 巴鲁克斯布隆伯格研究所 2020-01-03 CN claimed
CN-104918612-B Functionalized benzamide derivatives as antiviral agents against HBV infection 巴鲁克斯布隆伯格研究所 2019-10-25 CN claimed
CN-108947868-A The preparation process of one kind 2,4- difluorobenzonilyile 山东师范大学 2018-12-07 CN claimed
CN-108558674-A The production method of one kind 2,4- difluoroanilines 张金河 2018-09-21 CN claimed
EP-1773768-B1 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS INC (US) 2018-08-22 EP claimed
EP-1051176-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS Aventis Pharmaceuticals Products Inc. (US) 2000-11-15 EP claimed
WO-2000045635-A1 THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2000-08-10 WO claimed
EP-1022272-A1 SUBSTITUTED FUSED HETEROCYCLIC COMPOUNDS Sankyo Company Limited (JP) 2000-07-26 EP claimed
WO-2000037464-A2 4-(AMINOALKOXY)BENZOFURANS AS N-MYRISTOYLTRANSFERASE INHIBITORS BASILEA PHARMACEUTICA AG (CH) 2000-06-29 WO claimed
WO-2000025768-A1 OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF TREGA BIOSCIENCES, INC. (US) 2000-05-11 WO claimed
US-6017931-A Insecticidal compositions containing n-(substituted phenylmethyl)-4-[bis(substituted phenyl)methyl]piperidines FMC CORPORATION 2000-01-25 US claimed
WO-1999037304-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-07-29 WO claimed
US-5354495-A Homo- or copolymerizable through ethylenic unsaturation NIPPON PAINT CO., LTD. (JP) 1994-10-11 US claimed
EP-0177122-B1 ACRYLAMIDE DERIVATIVES Nippon Paint Co., Ltd. (JP) 1992-04-01 EP claimed
US-4935413-A ELASTICITY, ADHESION AND DISPERSIBILITY NIPPON PAINT CO., LTD. (JP) 1990-06-19 US claimed