Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 17/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30777475 | 0.75 | HDAC6 (0.52) | HDAC4HDAC6HDAC8HDAC1 | |
| SCHEMBL19014974 | 0.75 | HDAC6 (0.52) | HDAC4HDAC6HDAC8HDAC1 | |
| SCHEMBL24254418 | 0.75 | HDAC4 (0.48) | HDAC4HDAC6HDAC8HDAC1 | |
| SCHEMBL29395911 | 0.75 | HDAC4 (0.48) | HDAC4HDAC6HDAC8HDAC1 | |
| SCHEMBL22609172 | 0.73 | HDAC4 (0.47) | HDAC4HDAC6HDAC8HDAC1 | |
| SCHEMBL19030812 | 0.67 | HDAC4 (0.57) | HDAC4HDAC6HDAC8HDAC1 | |
| SCHEMBL18824381 | 0.66 | HDAC4 (0.66) | HDAC4HDAC6HDAC8HDAC1 | |
| SCHEMBL22626859 | 0.66 | HDAC4 (0.39) | HDAC4HDAC6HDAC8HDAC1 | |
| SCHEMBL14044148 | 0.66 | MEN1 (0.39) | — | |
| SCHEMBL19745563 | 0.66 | HDAC6 (0.51) | HDAC4HDAC6HDAC8HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035763-A1 | BORON CONTAINING COMPOUNDS AND THEIR USES | 5METIS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |