Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.68 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 2/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.42 |
| ▸ | CDK2 | P24941 | 3/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NEK2 | P51955 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | KIF20A | O95235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12500787 | 1.00 | MAP2K1 (0.68) | MAP2K1CNR2CAMKK2ADORA2AMTNR1A | |
| SCHEMBL16472206 | 0.85 | MAP2K1 (0.66) | MAP2K1CNR2CAMKK2ADORA2AMTNR1A | |
| SCHEMBL29526844 | 0.81 | MAP2K1 (1.00) | MAP2K1CNR2CAMKK2ADORA2AMTNR1A | |
| SCHEMBL1607007 | 0.81 | MAP2K1 (1.00) | MAP2K1CNR2CAMKK2ADORA2AMTNR1A | |
| Methoxymethane SCHEMBL28146835 | 0.81 | MAP2K1 (0.77) | MAP2K1CNR2CAMKK2ADORA2AMTNR1A | |
| SCHEMBL1940550 | 0.78 | MAP2K1 (0.73) | MAP2K1CNR2CAMKK2ADORA2AMTNR1A | |
| SCHEMBL30368631 | 0.78 | MAP2K1 (0.64) | MAP2K1CNR2CAMKK2ADORA2AMTNR1A | |
| SCHEMBL22558960 | 0.78 | MAP2K1 (0.43) | MAP2K1KMT2ACYP2C19HTR2C | |
| SCHEMBL2991525 | 0.77 | MAP2K1 (0.71) | MAP2K1CNR2CAMKK2ADORA2AMTNR1A | |
| SCHEMBL985214 | 0.77 | MAP2K1 (0.71) | MAP2K1CNR2CAMKK2ADORA2AMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3956327-A1 | CHIRAL INDOLE COMPOUNDS AND THEIR USE | Ariagen, Inc. (US) | 2022-02-23 | — | — | EP | disclosed |