Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 1.00 |
| ▸ | APP | P05067 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | HCAR3 | P49019 | 1/20 | 1.00 |
| ▸ | F7 | P08709 | 1/20 | 0.65 |
| ▸ | F3 | P13726 | 1/20 | 0.65 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.65 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.65 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.65 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.65 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.65 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.65 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.65 |
| ▸ | KMO | O15229 | 1/20 | 0.63 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.62 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.62 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Niacin SCHEMBL150011 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HCAR2APPGAAHCAR3 | |
| Niacin SCHEMBL29349574 | 1.00 | — | — | |
| Niacin SCHEMBL28292236 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HCAR2APPGAAHCAR3 | |
| Niacin SCHEMBL30844065 | 1.00 | — | — | |
| Niacin SCHEMBL3081560 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HCAR2APPGAAHCAR3 | |
| Niacin SCHEMBL1433 | 1.00 | — | — | |
| Niacin SCHEMBL23780926 | 0.98 | ALDH1A1 (0.95) | ALDH1A1HCAR2APPGAAHCAR3 | |
| Niacin SCHEMBL25235888 | 0.98 | ALDH1A1 (0.95) | ALDH1A1HCAR2APPGAAHCAR3 | |
| Niacin SCHEMBL25247085 | 0.98 | ALDH1A1 (0.95) | ALDH1A1HCAR2APPGAAHCAR3 | |
| Niacin SCHEMBL23780927 | 0.98 | ALDH1A1 (0.95) | ALDH1A1HCAR2APPGAAHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4559902-A2 | KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE | Imago Biosciences Inc. (US) | 2025-05-28 | — | — | EP | disclosed |
| EP-3256218-B1 | A KDM1A INHIBITOR AND ITS USE IN THERAPY | IMAGO BIOSCIENCES INC (US) | 2024-12-11 | — | — | EP | disclosed |
| CN-118973577-A | Apostistin for the treatment of multiple system atrophy | 施万生物制药研发IP有限责任公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-118613596-A | Biomarkers for detecting and distinguishing invasive prostate cancer from inert forms and treatment of invasive prostate cancer | 约翰霍普金斯大学 | 2024-09-06 | — | — | CN | disclosed |
| CN-111655859-B | Microorganism for producing putrescine and method for producing putrescine using the same | CJ第一制糖株式会社 | 2024-09-03 | — | — | CN | disclosed |
| CN-114569633-B | Intestinal selective chelators for the treatment and prevention of autism and related disorders | 轴向治疗公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-111225672-B | Mevalonate pathway inhibitor and pharmaceutical composition thereof | 清华大学 | 2023-09-29 | — | — | CN | disclosed |
| CN-115813923-A | Compounds for the treatment of neurogenic orthostatic hypotension | 施万生物制药研发IP有限责任公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-115770244-A | Compounds for the treatment of neurogenic orthostatic hypotension | 施万生物制药研发IP有限责任公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-114746092-A | D-amphetamine compounds, compositions, and methods of making and using the same | 肯法姆股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114746091-A | D-amphetamine compounds, compositions, and methods of making and using the same | 肯法姆股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-114569633-A | Gut-selective chelating agents for the treatment and prevention of autism and related disorders | 轴向治疗公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-110944650-B | Gut-selective chelating agents for the treatment and prevention of autism and related disorders | 轴向治疗公司 | 2022-03-04 | — | — | CN | disclosed |