Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 13/20 | 0.65 |
| ▸ | AVPR1A | P37288 | 8/20 | 0.65 |
| ▸ | OXTR | P30559 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5231674 | 0.99 | AVPR2 (0.63) | AVPR2AVPR1AOXTRMEN1KMT2A | |
| SCHEMBL1346004 | 0.86 | AVPR2 (0.69) | AVPR2AVPR1AOXTR | |
| Hydrochloric Acid SCHEMBL5236491 | 0.86 | AVPR2 (0.65) | AVPR2AVPR1AOXTRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4195564 | 0.85 | AVPR2 (0.68) | AVPR2AVPR1AOXTR | |
| SCHEMBL5233665 | 0.84 | AVPR2 (0.64) | AVPR2AVPR1AOXTRUSP2ALDH1A1 | |
| SCHEMBL2939627 | 0.83 | AVPR2 (0.66) | AVPR2AVPR1AOXTRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5234540 | 0.82 | MEN1 (0.66) | AVPR2AVPR1AOXTRMEN1KMT2A | |
| SCHEMBL5230483 | 0.82 | PDCD1 (0.44) | AVPR2AVPR1AMEN1KMT2AUSP2 | |
| SCHEMBL3456180 | 0.82 | MEN1 (0.72) | AVPR2AVPR1AMEN1KMT2AUSP2 | |
| SCHEMBL5237261 | 0.82 | AVPR2 (0.76) | AVPR2AVPR1AOXTRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778677-B1 | HETEROCYCLIC CONDENSED COMPOUNDS USEFUL AS ANTIDIURETIC AGENTS | VANTIA LTD (GB) | 2010-02-03 | — | — | EP | claimed |
| EP-1294698-A1 | FUSED AZEPINE DERIVATIVES AND THEIR USE AS ANTIDIURETIC AGENTS | FERRING B.V. (NL) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000626-A1 | FUSED AZEPINE DERIVATIVES AND THEIR USE AS ANTIDIURETIC AGENTS | FERRING B.V. (NL) | 2002-01-03 | — | — | WO | disclosed |