Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 14/20 | 0.66 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.66 |
| ▸ | OXTR | P30559 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2937767 | 0.87 | AVPR2 (0.64) | AVPR2AVPR1AOXTR | |
| SCHEMBL2939629 | 0.83 | AVPR2 (0.65) | AVPR2AVPR1AOXTRMEN1KMT2A | |
| SCHEMBL3456180 | 0.83 | MEN1 (0.72) | AVPR2AVPR1AMEN1KMT2A | |
| SCHEMBL5243307 | 0.82 | AVPR2 (0.80) | AVPR2AVPR1AOXTR | |
| Hydrochloric Acid SCHEMBL5231674 | 0.82 | AVPR2 (0.63) | AVPR2AVPR1AOXTRMEN1KMT2A | |
| SCHEMBL4895521 | 0.82 | AVPR2 (0.70) | AVPR2AVPR1AOXTRMEN1KMT2A | |
| SCHEMBL7019375 | 0.81 | AVPR2 (0.73) | AVPR2AVPR1AOXTR | |
| SCHEMBL5461713 | 0.80 | MEN1 (0.68) | AVPR2AVPR1AMEN1KMT2A | |
| SCHEMBL5474789 | 0.79 | AVPR2 (0.62) | AVPR2AVPR1AMEN1KMT2A | |
| SCHEMBL7350038 | 0.78 | AVPR1A (0.66) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778677-B1 | HETEROCYCLIC CONDENSED COMPOUNDS USEFUL AS ANTIDIURETIC AGENTS | VANTIA LTD (GB) | 2010-02-03 | — | — | EP | claimed |