Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.48 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | GGT1 | P19440 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.39 |
| ▸ | GNPAT | O15228 | 1/20 | 0.39 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29669470 | 0.96 | FOLH1 (0.58) | FOLH1CPB2GSRRNPEPMMP2 | |
| SCHEMBL29390540 | 0.93 | FOLH1 (0.59) | FOLH1CPB2GSRRNPEPMMP2 | |
| SCHEMBL29894486 | 0.93 | FOLH1 (0.59) | FOLH1CPB2GSRRNPEPMMP2 | |
| SCHEMBL29585858 | 0.90 | FOLH1 (0.49) | FOLH1CPB2GSRRNPEPMMP2 | |
| SCHEMBL27583930 | 0.90 | FOLH1 (0.49) | FOLH1CPB2GSRRNPEPMMP2 | |
| SCHEMBL6373385 | 0.89 | FOLH1 (0.47) | FOLH1CPB2GSRRNPEPMMP2 | |
| SCHEMBL1705338 | 0.89 | FOLH1 (0.47) | FOLH1CPB2GSRRNPEPMMP2 | |
| SCHEMBL1705339 | 0.89 | FOLH1 (0.47) | FOLH1CPB2GSRRNPEPMMP2 | |
| SCHEMBL31285810 | 0.88 | FOLH1 (0.44) | FOLH1CPB2GSRRNPEPMMP2 | |
| SCHEMBL30427337 | 0.88 | FOLH1 (0.44) | FOLH1CPB2GSRRNPEPMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035843-A1 | TOPOISOMERASE INHIBITORS | NANOMEDICINE INNOVATION CENTER, LLC (US) | 2022-02-17 | — | — | WO | disclosed |